Molecular and Integrative Signal Transduction study section [MIST]

[MIST Membership Roster] [MIST Meeting Rosters]


MIST reviews focus on basic molecular mechanisms of cellular signaling. The applications are on the biochemical and structural mechanisms of signal transduction, including G-proteins, seven-transmembrane protein (7TM) coupled receptors, and their regulation. MIST also reviews the associated kinases, phosphatases and lipid signaling mechanisms and cross-talk with other pathways. Integrative studies may involve a variety of organisms that advance the field whether uni- or multi-cellular, bacterial or mammalian. Specific Areas include:

 

  • Biochemical and structural mechanisms of receptor signal
    transduction, including G-proteins and 7TM receptors.
  • Protein-protein interactions among signaling molecules.
  • Serine and tyrosine protein kinases associated with signal transduction mechanisms.
  • Protein phosphatases associated with signal transduction mechanisms.
  • Second messengers including lipid signaling molecules.
  • Related metabolic studies including drugs and inhibitors.
  • Regulatory mechanisms controlling signaling including regulator of G-protein signaling (RGS) proteins.
  • Calcium signaling mechanisms including structure/regulation of calcium channels and cellular organization of calcium signals.
  • Computer simulations and modeling of signaling complexes and pathway components.

Study sections with most closely related areas or similar science listed in rank order are:

Cellular Signaling and Regulatory Systems [CSRS]
Vascular Cell and Molecular Biology [VCMB]
Cellular and Molecular Immunology A [CMIA]
Cellular and Molecular Immunology B [CMIB]
Cellular Aspects of Diabetes and Obesity [CADO]



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