Neurotransporters, Receptors, Channels and Calcium Signaling Study Section [NTRC]

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The Neurotransporters, Receptors, Channels and Calcium Signaling [NTRC] Study Section reviews studies of signal transduction pathways in neurons, muscles, and other excitable cells with particular emphasis on cellular and molecular regulation, physiology and functional consequences. This includes studies of calcium physiology; regulation of ionic gradients, ion pumps and molecular transporters; ion channels; ligand-gated channels; receptors; and transduction molecules. Studies may employ molecular, cellular, biochemical, electrophysiological, and imaging approaches. Emphasis is on fundamental cellular mechanisms, including those relevant to disease processes. Specific areas covered by NTRC:

  • Intracellular regulation of calcium and calcium signaling; calcium channels, calcium storage, homeostasis, and buffering; calcium as a second messenger.
  • Ion pumps, ion exchangers, and neurotransmitter transporters; electrochemical coupling; maintenance of ionic gradients; membrane properties and electrodynamics.
  • Ion channels and neurotransmitter receptors; gap junctions; electrophysiological and imaging studies involving integration and propagation of electrical signals within the context of cellular physiology; interactions with second messenger systems; regulation and modulation of ion channels and receptors, including ionotropic and metabotropic receptors; mechanisms underlying synaptic plasticity such as long term potentiation, long term depression and paired pulse facilitation.
  • Synthesis, genetic regulation, transcription, translation and post-translational modification of transduction molecules; genetic regulation, transcription/translation, post-translational modification; localization, assembly, trafficking, turnover, and degradation of receptors, channels, transporters, and transduction machinery.

Study Sections with most closely related areas of science listed in rank order are:

Biophysics of Neural Systems [BPNS]
Synapses, Cytoskeleton and Trafficking [SYN]  
Molecular Neuropharmacology and Signaling [MNPS]

Clinical Neuroplasticity and Neurotransmitters [CNNT]
Neurobiology of Learning and Memory [LAM]



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