Skip to Content
United States National Library of Medicine National Institutes of Health

Fact Sheet
Chemical Carcinogenesis Research Information System (CCRIS)

CCRIS is a toxicology data file of the National Library of Medicine's (NLM) Toxicology Data Network (TOXNET®). It is a scientifically evaluated and fully referenced data bank, developed and maintained by the National Cancer Institute (NCI). It contains over 9,000 chemical records with carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition test results. Data are derived from studies cited in primary journals, current awareness tools, NCI reports, and other special sources. Test results have been reviewed by experts in carcinogenesis and mutagenesis.

Web Access/Searching

CCRIS is accessible, free of charge, via TOXNET at: http://toxnet/

Users can search by chemical or other name, chemical name fragment, Chemical Abstracts Service Registry Number (RN), and/or subject terms. Search results can easily be viewed, printed or downloaded. Search results are displayed in relevancy ranked order. Users may select to display any combination of data from the following broad groupings:

(a) Carcinogenicity Studies
(b) Tumor Promotion Studies
(c) Mutagenicity Studies
(d) Tumor Inhibition Studies

Users can easily conduct their CCRIS search strategy against other databases: Hazardous Substances Data Bank®, Integrated Risk Information System, GENE-TOX, TOXLINE®, and ChemIDplus®.

Further Information

For detailed information about CCRIS or TOXNET, contact:

CCRIS Representative
Specialized Information Services
National Library of Medicine
Two Democracy Plaza, Suite 510
6707 Democracy Boulevard, MSC 5467
Bethesda, MD 20892-5467
Telephone (30l) 496-1131
FAX: (301) 480-3537

For information on NLM services, contact:

National Library of Medicine
Customer Service
8600 Rockville Pike
Bethesda, MD 20894
Telephone: 1-888-FINDNLM (1-888-346-3656) or (301) 594-5983

A complete list of NLM Fact Sheets is available at:
(alphabetical list)
(subject list):

Or write to:

Office of Communications and Public Liaison
National Library of Medicine
8600 Rockville Pike
Bethesda, Maryland 20894

Phone: (301) 496-6308
Fax: (301) 496-4450

Last reviewed: 09 May 2008
Last updated: 09 May 2008
First published: 01 January 1994
Metadata| Permanence level: Permanent: Stable Content