[CMIB Membership Roster] [CMIB Meeting Rosters]

The Cellular and Molecular Immunology B Study Section reviews applications concerned with the function and structure of the adaptive immune system. Emphasis is on the activation, developmental, differentiation and interactions of the cells and organs of immune system on the molecular and cellular levels. The topics addressed include:

• molecular and cellular regulation during early and peripheral lymphoid cell development such as T cells, B cells, NK cells, NKT cells, regulatory T cells, and myelo/hematopoiesis and apoptosis involved during these processes.
• mechanisms of lymphoid repertoire formation during development, activation, differentiation and aging especially VDJ recombination in T cell receptor, B cell receptor and immunoglobulin (Ig) genes, isotype switching and somatic hypermutation of Ig genes.
• initiation and recall of adaptive immune responses, including antigen processing and presentation, interactions with innate immunity, signal transduction and transcriptional regulation in lymphocyte activation, and cytokine signaling and function.
• dynamics of the immune response, including homeostasis, regulation and memory in primary and secondary lymphoid organs (e.g. bone marrow, thymus, lymph nodes, spleen, liver, GALT).
• mechanisms of disorders during lymphocyte development, activation and differentiation that lead to immunodeficiency diseases.
• comparative immunology in non-mammalian animals.

Study sections with the most closely related areas of science listed in rank order are:

Cellular and Molecular Immunology A [CMIA] 
Hematopoiesis [HP] 
Cellular Mechanisms in Aging and Development [CMAD] 
Hypersensitivity, Autoimmune, and Immune-mediated Diseases [HAI] 
Transplantation, Tolerance, and Tumor Immunology [TTT]