Sec. 654.100 Dimethyl Sulfoxide (DMSO) for Animal Use (CPG 7125.23)
BACKGROUND:
DMSO is a by-product of the paper industry and is able to carry some drugs rapidly
through the skin. Industrial grade DMSO is widely available for various non-medical uses
such as paint remover and antifreeze. The *Center for* Veterinary Medicine has received
inquiries concerning the status of DMSO for use in animals, probably prompted by the
approval of DMSO for human use in April 1978. The product is a new animal drug with
approved uses only in horses and dogs (See 21 CFR 524.660, 524.981d and 524.981e).
POLICY:
DMSO used for any veterinary purposes other than approved uses reflected in the CFR is a new animal drug without an approved new animal drug
application (NADA). As such, it is adulterated under Section 501(a)(5) of the Act.
NOTE: At least one state (Florida, Bill No. S. 699) has passed legislation (1978) that prohibits interference with the use of DMSO.
*Material between asterisks is new or revised.*
Issued: 10/1/80
Revised: 3/95