Study Results & Research Projects

Summaries & Associations of Study Results

Positive in Micronucleus tests and positive in only one rodent species in the 2-year Carcinogenesis Study

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http://ntp.niehs.nih.gov/go/14776

Positive in Micronucleus (Peripheral Blood) tests and positive in only one rodent species in the 2-year Carcinogenesis Study

 Levels of Evidence of Carcinogenicity
TR No.Chemical MN Route MRFR MM FM
479 COCONUT OIL ACID DIETHANOLAMINE CONDENSATE +/+ Topical Application NE EE CE CE
513 DECALIN W+/- Inhalation CE NE NE EE
486 ISOPRENE +/+,+,+/+ Inhalation CE SE   
527 LEUCOMALACHITE GREEN NA/+ Dosed-Feed EE EE   SE
515 PROPYLENE GLYCOL MONO-T-BUTYL ETHER -/W+ Inhalation EE NE CE CE
027 1,1,2,2-TETRACHLOROETHANE ?/+,+/+ Gavage E N P P
510 URETHANE +,-,+/+,+/+ Dosed-Water     CE CE

CE or P = Clear Evidence, SE = Some Evidence, EE or E = Equivocal Evidence, NE or N = No Evidence, IS = Inadequate Experiment

Micronucleus results: +:Positive, -:Negative, W:Weak, e:Equivocal, ?:Inconclusive, *:Nonstandard protocol, /:Male/Female