National Toxicology Program

CASRN: TEFDIOXINMIX

Formula: N/A

Synonyms/Common Names:

• DIOXIN MIXTURE (TOXIC EQUIVALENCY FACTOR EVALUATION)
• TOXIC EQUIVALENCY FACTOR EVALUATION (DIOXIN MIXTURE)

Secondary:

• 57465-28-8 - 3,3,4,4,5-Pentachlorobiphenyl
• 57117-31-4 - 2,3,4,7,8-Pentachlorodibenzofuran
• 57117-31-4 - TEF evaluation (PECDF (Pentachlorodibenzofuran))
• 1746-01-6 - TEF evaluation (TCDD)
• 57465-28-8 - TEF transgenics (PCB 126)
• 57117-31-4 - TEF transgenics (PECDF)
• 1746-01-6 - TEF transgenics (TCDD)
• 1746-01-6 - 2,3,7,8-Tetrachlorodibenzo-p-dioxin
• 57465-28-8 - Toxic equivalency factor evaluation ((PCB 126) 3,3',4,4',5-pentachlorobiphenyl)
• 1746-01-6 - Transgenic Model Evaluation (2,3,7,8-Tetrachlorodibenzodioxin)

Long-Term Carcinogenicity

• 2-YEAR (Gavage)  (C96007B) Report Complete 
  • TR-526 (NTIS No. PB2007-103747)  (Peer Review 02/17/2004)
    Toxicology and Carcinogenesis Studies of a Mixture of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) (CAS No. 1746-01-6), 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4), and 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in Female Harlan Sprague-Dawley Rats (Gavage Studies)
  • Rats: Sprague Dawley
  • Carcinogenesis Results
  • Female Rats Clear Evidence 
  • Dose: FEMALE RATS ONLY: 0, (TCDD) 3.3, 7.3, 15.2, OR 33 NG/KG; (PeCDF) 6.6, 14.5, 30.4, OR 66 NG/KG; (PCB 126) 33.3, 73.3, 153, OR 333 NG/KG; 100/DOSE