National Toxicology Program

CASRN: 309-00-2

Formula: C12 H8 CL6

Synonyms/Common Names:

• ENT 15949

Known Uses:

INSECTICIDE

Short-Term Toxicity

• 14-Day (Dosed-Feed)  (C00044) Completed 
  • NTIS No. PB275666  (Peer Review 09/26/1977)
    Citation: Bioassays of Aldrin and Dieldrin for Possible Carcinogenicity (CAS No. 309-00-2) (CAS No. 60-57-1)
  • Rats: Osborne Mendel; Mice: B6C3F1
• 13-Week (Dosed-Feed)  (C00044) Completed 
  • NTIS No. PB275666  (Peer Review 09/26/1977)
    Citation: Bioassays of Aldrin and Dieldrin for Possible Carcinogenicity (CAS No. 309-00-2) (CAS No. 60-57-1)
  • Rats: Osborne Mendel; Mice: B6C3F1
  • Dose: R: 0,40,320, M: 0,2.5,80 PPM/5 PER GROUP

Long-Term Carcinogenicity

• 2-Year (Dosed-Feed)  (C00044) Report Complete 
  • TR-021 (NTIS No. PB275666)  (Peer Review 09/26/1977)
    Bioassays of Aldrin and Dieldrin for Possible Carcinogenicity (CAS No. 309-00-2) (CAS No. 60-57-1)
  • Rats: Osborne Mendel; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Equivocal 
  • Female Rats Equivocal 
  • Male Mice Positive 
  • Female Mice Negative 
  • Dose: R:0,30,60 MM:0,4,8 FM:0,3,6 PPM/50 PER GROUP

Genetic Toxicology

• Salmonella  (127997) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
  •  Negative