National Toxicology Program

CASRN: 13366-73-9

Formula: C12-H8-CL6-0

Synonyms/Common Names:

• (1AALPHA,1BBETA,2ALPHA,2ABETA,4BETA,5BETA,5ABETA,5BBETA,6ALPHA,6AALPHA)-2A,3,3,4,5,5A-HEXACHLORDECAHYDRO-2,4,6-METHENO-2-CYCLOPENTA(4,5)PENTALENO(1,2-B)OXIRENE (9CI)

Known Uses:

PHOTOCHEMICAL CONVERSION PRODUCT OF PESTICIDE DIELDRIN

Short-Term Toxicity

• 14-Day (Dosed-Feed)  (C00599) Completed 
  • NTIS No. PB274393  (Peer Review 07/25/1977)
    Citation: Bioassay of Photodieldrin for Possible Carcinogenicity (CAS No. 13366-73-9)
  • Rats: Osborne Mendel; Mice: B6C3F1
• 13-Week (Dosed-Feed)  (C00599) Completed 
  • NTIS No. PB274393  (Peer Review 07/25/1977)
    Citation: Bioassay of Photodieldrin for Possible Carcinogenicity (CAS No. 13366-73-9)
  • Rats: Osborne Mendel; Mice: B6C3F1
  • Dose: R: 0,2.5,80 (AVG), M: 0,.01,.32 (AVG) PPM/10 PER GROUP

Long-Term Carcinogenicity

• 2-Year (Dosed-Feed)  (C00599) Report Complete 
  • TR-017 (NTIS No. PB274393)  (Peer Review 07/25/1977)
    Bioassay of Photodieldrin for Possible Carcinogenicity (CAS No. 13366-73-9)
  • Rats: Osborne Mendel; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Negative 
  • Female Rats Negative 
  • Male Mice Negative 
  • Female Mice Negative 
  • Dose: MR: 0,5,10, FR: 0,3,4,7.5 (AVG), M: 0,.32,.64 PPM/50 PER GROUP

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (934568) Completed 
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Positive 
• Salmonella  (543366) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Positive