National Toxicology Program

CASRN: 26628-22-8

Formula: N3-Na

Known Uses:

HERBICIDE, PESTICIDE, REAGENT, DIAGNOSTIC MEDICINE PRESERVATIVE, FUNGICIDE, FUMIGANT (HSDB 1990)

Short-Term Toxicity

• 14-Day (Gavage)  (C06462) Completed 
  • NTIS No. PB92-135615  (Peer Review 04/25/1990)
    Citation: Toxicology and Carcinogeneis Studies of Sodium Azide (CAS No. 26628-22-8) in F344 Rats (Gavage Studies)
  • Rats: F344/N
• 13-Week (Gavage)  (C06462) Completed 
  • NTIS No. PB92-135615  (Peer Review 04/25/1990)
    Citation: Toxicology and Carcinogeneis Studies of Sodium Azide (CAS No. 26628-22-8) in F344 Rats (Gavage Studies)
  • Rats: F344/N
  • Dose: RATS ONLY:0,.063,4 MG/ML/10 PER GROUP

Long-Term Carcinogenicity

• 2-YEAR (Gavage)  (C06462) Report Complete 
  • TR-389 (NTIS No. PB92-135615)  (Peer Review 04/25/1990)
    Toxicology and Carcinogeneis Studies of Sodium Azide (CAS No. 26628-22-8) in F344 Rats (Gavage Studies)
  • Rats: F344/N
  • Carcinogenesis Results
  • Male Rats No Evidence 
  • Female Rats No Evidence 
  • Dose: RATS ONLY:0,5,10 MG/KG/60 PER GROUP

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (166603) Completed 
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Positive 
• Salmonella (NCI)  (N-9164) Completed 
  • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
  • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escerichia coli using a standardized protocol Environ. Mutagen. Vol. 6 (Suppl 2) (1985) 1-251
  • Salmonella-NCI  Positive 
• Salmonella  (201201) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
  • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
  •  Positive 
• Salmonella  (A90612) Completed 
  • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
  •  Positive