Testing Status of Agents at NTP
Monochloroacetic acid
CASRN: 79-11-8
Formula: C2-H3-CL-O2
Synonyms/Common Names:
- ACETIC ACID, CHLORO- (8CI)(9CI)
Known Uses:
CHEMICAL INTERMEDIATE IN THE MANUFACTURE OF VARIOUS DYES AND OTHER ORGANIC MATERIALS. (TDB)
Short-Term Toxicity
- 14-Day (Gavage)
(C60231) Completed
- NTIS No. PB92-189372
(Peer Review 11/20/1990)
Citation: Toxicology and Carcinogenesis Studies of Monochloroacetic Acid (CAS No. 79-11-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB92-189372
(Peer Review 11/20/1990)
- 13-Week (Gavage)
(C60231) Completed
- NTIS No. PB92-189372
(Peer Review 11/20/1990)
Citation: Toxicology and Carcinogenesis Studies of Monochloroacetic Acid (CAS No. 79-11-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,30,150, M: 0,25,200 MG/KG/40 PER GROUP
- NTIS No. PB92-189372
(Peer Review 11/20/1990)
Long-Term Carcinogenicity
- 2-YEAR (Gavage)
(C60231) Report Complete
- TR-396 (NTIS No. PB92-189372)
(Peer Review 11/20/1990)
Toxicology and Carcinogenesis Studies of Monochloroacetic Acid (CAS No. 79-11-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats No Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: R: 0,15,30; M: 0,50,100 MG/KG/70 & 60 PER GROUP RESPECTIVELY
- TR-396 (NTIS No. PB92-189372)
(Peer Review 11/20/1990)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(265221) Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Chromosome Aberation Negative
- Sister Chromatid Exchange Positive
- Drosophila
(255229) Completed
- Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
- Reciprocal Translocation/Sex-Linked Recessive Lethal Inconclusive
- Mouse Lymphoma
(486223) Completed
- Citation: McGregor, D.B., Martin, R., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I. Results for nine compounds. Environ. Mutagen. Vol. 9 (1987) 143-160
- Positive
- Salmonella
(910172) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative
- Salmonella
(A15096) Completed
- Negative
Web page last updated on November 24, 2008