National Toxicology Program

CASRN: 55-31-2

Related: EPINEPHRINE (CAS 51-31-2)

Formula: C9-H13-N-O3.CL-H

Synonyms/Common Names:

• (R)-4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-1,2-BENZENEDIOL HYDROCHLORIDE (9CI)

Known Uses:

ADRENERGIC, VASOCONSTRICTOR, CARDIAC STIMULANT, BRONCHODILATOR

Short-Term Toxicity

• 14-Day (Inhalation)  (C55663) Completed 
  • NTIS No. PB91-142323  (Peer Review 11/20/1989)
    Citation: Toxicology and Carcinogenesis Studies of l-Epinephrine Hydrochloride (CAS No. 55-31-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Inhalation)  (C55663) Completed 
  • NTIS No. PB91-142323  (Peer Review 11/20/1989)
    Citation: Toxicology and Carcinogenesis Studies of l-Epinephrine Hydrochloride (CAS No. 55-31-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: 0,2.5,40 MG/M3/10 PER GROUP

Long-Term Carcinogenicity

• 2-YEAR (Inhalation)  (C55663) Report Complete 
  • TR-380 (NTIS No. PB91-142323)  (Peer Review 11/20/1989)
    Toxicology and Carcinogenesis Studies of l-Epinephrine Hydrochloride (CAS No. 55-31-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Inadequate Study 
  • Female Rats Inadequate Study 
  • Male Mice Inadequate Study 
  • Female Mice Inadequate Study 
  • Dose: R: 0,1.5,5.0, M: 0,1.5,3.0 MG/M3/50 PER GROUP