Summaries & Associations of Study Results
Levels from TR-545 Genistein
Target Organs and Levels of Evidence
NTP Technical Report Number 545
Produced from Chemtrack Database 10/17/06
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
|
ENDOCRINE DISRUPTOR (GENISTEIN)
446-72-0 |
06/12/06 | ANTINEOPLASTIC AGENT; GROWTH INHIBITOR; NATURALLY-OCCURRING PHYTOESTROGEN FOUND IN SEVERAL PLANTS INCLUDING SOY PRODUCTS. NUTRITIONAL AND PHARMACEUTICAL APPLICATIONS. | Dosed-Feed (5K96) | National Center for Toxicological Research |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| F1C (MALE): NO EVIDENCE | ||||
| F1C (FEMALE): SOME EVIDENCE | MAMMARY GLAND: ADENOMA OR ADENOCARCINOMA 9/54 4/50 8/50 16/49 | |||
| PITUITARY GLAND: ADENOMA OR CARCINOMA 38/54 40/50 34/50 46/49 | ||||
| OTHER CONSIDERATIONS: | MAMMARY GLAND: FIBROADENOMA 32/54 27/50 28/50 12/49 | |||
| F1T140 (MALE): NO EVIDENCE | ||||
| F1T140 (FEMALE): EQUIVOCAL EVIDENCE | ||||
| MAY HAVE BEEN RELATED: | PITUITARY GLAND: ADENOMA OR CARCINOMA 38/54 32/49 40/50 44/50 | |||
| F3T21 (MALE): NO EVIDENCE | ||||
| F3T21 (FEMALE): EQUIVOCAL EVIDENCE | ||||
| MAY HAVE BEEN RELATED: | MAMMARY GLAND: ADENOMA OR ADENOCARCINOMA 7/53 8/49 11/50 13/50 | |||
Web page last updated on October 26, 2006
