Summaries & Associations of Study Results
TR-006 Nitrilotriacetic acid (NTA)
Target Organs and Levels of Evidence
NTP Technical Report Number 006
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| NITRILOTRIACETIC ACID (NTA) 139-13-9 |
03/25/77 | CHELATING AGENT; DETERGENTS; WATER AND TEXTILE TREATMENT; METAL PLATING; PULP AND PAPER PROCESSING | Dosed-Feed R: 0,7500,15000, M: 0,2500,5000,7500,15000 PPM/50 PER GROUP | Litton Bionetics, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | KIDNEY TUBULAR CELL: ADENOMA OR ADENOCARCINOMA | |||
| URETER (ADENOMA OR PAPILLOMA) | ||||
| FR: POSITIVE | URINARY BLADDER (TRANSITIONAL CELL CARCINOMA) | |||
| MM: POSITIVE | KIDNEY TUBULAR CELL: ADENOCARCINOMA | |||
| FM: POSITIVE | KIDNEY TUBULAR CELL: ADENOCARCINOMA | |||
| NITRILOTRIACETIC ACID TRISODIUM MONOHYDRATE 18662-53-8 |
03/25/77 | DETERGENTS | Dosed-Feed R: 0,7500,15000, M: 0,2500,5000 PPM/50 PER GROUP | Litton Bionetics, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: EQUIVOCAL | KIDNEY TRANSITIONAL CELL: PAPILLOMA | |||
| KIDNEY TUBULAR CELL: ADENOCARCINOMA | ||||
| FR: EQUIVOCAL | URINARY BLADDER (TRANSITIONAL CELL CARCINOMA) | |||
| MM: NEGATIVE | ||||
| FM: NEGATIVE | ||||
| NITRILOTRIACETIC ACID TRISODIUM MONOHYDRATE 18662-53-8 |
03/25/77 | DETERGENTS | Dosed-Feed 0,200,2000,20000 PPM/48 PER GROUP | SRI International |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | KIDNEY TRANSITIONAL CELL: CARCINOMA | |||
| KIDNEY TUBULAR CELL: ADENOCARCINOMA OR CARCINOMA | ||||
| URETER (TRANSITIONAL CELL CARCINOMA) | ||||
| FR: POSITIVE | KIDNEY TUBULAR CELL: ADENOMA OR ADENOCARCINOMA | |||
| URETER (TRANSITIONAL CELL CARCINOMA) | ||||
| URINARY BLADDER (TRANSITIONAL CELL CARCINOMA) | ||||
Web page last updated on February 10, 2006
