The Systemic Injury by Environmental Exposure (SIEE) Special Emphasis Panel reviews applications related to the pharmacological and toxicological mechanisms whereby xenobiotics affect distinct organ systems, other than the digestive and nervous systems. Specifically, SIEE reviews applications related to the cardiovascular, musculoskeletal, hematopoietic, renal, respiratory/pulmonary, immune, endocrine and reproductive systems. Other areas included are skin, oral, dental and craniofacial tissues, pregnancy and development.

Specific areas covered by SIEE:
 

• Mechanisms of action of xenobiotics, including toxicological and/or pharmacological effects.
• Development of animal models that study the effects of xenobiotics.
• Molecular basis for susceptibility to xenobiotics-induced toxicity and disease (e.g., pharmacogenetics, pharmacogenomics, toxicogenetics, toxicogenomics).
• Identification of biomarkers of xenobiotics-induced toxicity.

Study sections with most closely related areas of similar science listed in rank order are:

Xenobiotic and Nutrient Disposition and Action [XNDA] 
Infectious Diseases, Reproductive Health, Asthma and Pulmonary Conditions [IRAP] 
Cancer Etiology Study Section [CE] 
Chemo/Dietary Prevention Study Section [CDP] 
Integrative Nutrition and Metabolic Processes [INMP]