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Haemophilus influenzae (Invasive Disease)
(H. influenzae)
1997 Case Definition
The 1997 case definition appearing on this page was previously published in the 1990
MMWR Recommendations and Reports titled Case Definitions for Public Health Surveillance [MMWR 1990;39(RR13)]
(available at http://www.cdc.gov/mmwr/preview/mmwrhtml/00025629.htm).
Thus, the 1990 and 1997 versions of the case definition are identical.
Clinical description
Invasive disease caused by Haemophilus influenzae may
produce any of several clinical syndromes, including meningitis,
bacteremia, epiglottitis, or pneumonia.
Laboratory criteria for diagnosis
-
Isolation of H. influenzae from a normally
sterile site (e.g., blood or cerebrospinal fluid [CSF] or, less
commonly, joint, pleural, or pericardial fluid)
Case classification
Probable: a clinically
compatible case with detection of H. influenzae type b antigen
in CSF
Confirmed: a clinically compatible case that
is laboratory confirmed
Comment
Positive antigen test results from urine or serum samples
are unreliable for diagnosis of H. influenzae disease.
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