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Cryptosporidiosis (Cryptosporidium parvum)
1998 Case Definition
Clinical description
An illness caused by the protozoan Cryptosporidium
parvum and characterized by diarrhea, abdominal cramps,
loss of appetite, low-grade fever, nausea, and vomiting. Infected
persons may be asymptomatic. The disease can be prolonged and
life-threatening in severely immunocompromised persons.
Laboratory criteria for diagnosis
Laboratory-confirmed cryptosporidiosis shall be
defined as the detection—in symptomatic or asymptomatic
persons—of Cryptosporidium
- oocysts in stool by microscopic examination, or
- in intestinal fluid or small-bowel biopsy specimens, or
- oocyst or sporozoite antigens by immunodiagnostic methods,
e.g., ELISA, or
- by PCR techniques when routinely available, or
- demonstration of reproductive stages in tissue preparations.
Case classification
Confirmed, symptomatic:
a laboratory-confirmed case associated with one of the symptoms
described above
Confirmed, asymptomatic: a laboratory-confirmed
case associated with none of the above symptoms
See also:
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