SBIR none HIV-Vaccine Development [IMM-K]

[IMM-K Roster]

The Immunologic Sciences Special Emphasis Panel ZRG1 IMM-K reviews grant applications from the small business community in the area of non-HIV microbial vaccine development for the Small Business Innovation Research (SBIR) and the Small Business Technology Transfer Research (STTR) Programs.  Applications from small businesses that address basic and applied studies in the design, development, production, and evaluation of candidate vaccines against microbial-caused diseases are appropriate for review in this panel.  The applications should project the development of a product, process, service, or platform technology that can be developed as a commercial venture.  ZRG1 IMM-K also reviews the adaptation or fabrication of vaccine delivery systems and adjuvant systems.  The panel does not review grant applications proposing development of vaccines against HIV or AIDS.  Specific areas covered by ZRG1 IMM-K are as follows:

  • All types of vaccines against diseases caused by bacteria, fungi, viruses (except HIV), and parasites, including live attenuated viral/bacterial vaccines, inactivated whole-organism vaccines, subunit vaccines, recombinant protein-based vaccines, vector-based vaccines, polysaccharide vaccines, conjugate vaccines, DNA vaccines, synthetic vaccines, mimetic vaccines, plant-derived vaccines, combination vaccines, etc.
  • Vaccine design: antigen selection, epitope selection and design, use of adjuvant, use of vectors and chimeric carriers, vaccine formulation.
  • Vaccine evaluation: immunogenicity, efficacy, safety, longevity, and use of animal models.
  • Vaccine delivery systems: bacterial and viral vectors, chimreic vaccine carriers, liposome, nanoparticles.
  • Adjuvants for specific vaccines.
  • Vaccine production: production methodologies, process development/optimization/scale-up, GMP production and clinical material manufacturing.
  • Other vaccine technologies, e.g. vaccine storage stability, pathogen inactivation methodologies, new cell substrates to produce vaccines. 


IRGs with the most closely related areas of science listed in rank order are:

Infectious Diseases and Microbiology [IDM] IRG 
Musculoskeletal, Oral and Skin Sciences [MOSS] IRG  
Oncology 1 - Basic Translational IRG 
Oncology 2 - Translational Clinical IRG  
Cardiovascular and Respiratory Sciences IRG  
AIDS and Related Research [AARR] IRG   



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