Advisory Board & Committees
BSC Final Agenda: February 5-6, 1998
| February 5 | ||
| 8:45 - 9:00 a.m | Welcomeand Director's Report | Dr. K. Olden, NIEHS |
| 9:00 - 9:15 a.m. | Introduction- purpose of meeting | Dr. G. Lucier, NIEHS |
| 9:15 - 9:45 a.m. | Historyand rationale for using transgenic animals to identifycarcinogens | Dr. R. Tennant, NIEHS |
| 9:45 - 10:15 a.m. | Studieswith the p53def mouse model | Dr. J.French, NIEHS |
| 10:15 - 10:35 a.m. | Break | |
| 10:35 - 10:55 a.m. | Studieswith the Tg.AC mouse model | Dr. J. Spalding, NIEHS |
| 10:55 - 11:20 a.m. | Molecularand cellular Tg.AC studies | Dr. R. Cannon, NIEHS |
| 11:20 - 11:50 a.m. | Resultsof NTP transgenic evaluations | Dr. W. Eastin, NIEHS |
| 11:50 - 12:50 p.m. | Lunch | |
| 12:50 - 1:30 p.m. | Studieswith the rasH2 mouse model | Dr. R. Maronpot, NIEHS Dr. K. Mitsumori, National Institute of Health Sciences, Tokyo |
| 1:30 - 2.00 p.m. | Summaryof model studies evaluation | Dr. J. Bucher, NIEHS |
| 2:00 - 2:30 p.m. | Transgenicstudies and risk assessment | Dr. C. Portier, NIEHS |
| 2:30 - 2:50 p.m. | Break | |
| 2:50 - 3:10 p.m. | FDA perspectiveon transgenic models | Dr. J. Contrera, FDA |
| 3:10 - 3:30 p.m. | EPA perspectiveon transgenic models | Dr. V. Dellarco, EPA |
| 3:30 - 4:00 p.m. | Publiccomments |
|
| February 6 |
||
| 8:45 - 9:20 a.m. | Reportof the Director, ETP | Dr. G. Lucier |
| 9:20 - 10:00 a.m. | Reportsof Committee Activities: | |
| - Report on CarcinogensSubcommittee | Dr. C. Jameson, NIEHS | |
| - Technical Reports Review Subcommittee | Dr. R. Hailey, NIEHS | |
| - Interagency CoordinatingCommittee on the Validation of AlternativeMethods(ICCVAM) - Meeting to DiscussNTPCenter for the Evaluationof AlternativeToxicological Methods | Dr. W. Stokes, NIEHS | |
| 10:00 - 10:20 a.m. | Break |
|
| 10:20 - 10:40 a.m. | ConceptReview | |
| - Pathology Support forthe National Toxicology Program | Dr. R. Herbert, NIEHS | |
| 10:40 - 11:50 a.m. | ChemicalsNominated and Reviewed For NTP Study by the InteragencyNIEHS Committee for Chemical Evaluation and Coordination (ICCEC)on August 15 and December 11, 1997 | Dr. H. Matthews, |
| Adjournment |
| Eula Bingham, Ph.D. (6/99) Professor Department of Environmental Health, M.L. 056 University of Cincinnati College of Medicine Cincinnati, OH 45267-0001 (Occupational and Environmental Health) |
James S. Bus, Ph.D. (6/99) Technical Director Health & Environmental Sciences Dow Chemical Company 1803 Building Midland, MI 48674 (Toxicology, Chemical Disposition)< |
| Gary P. Carlson, Ph.D. (6/99) Professor School of Health Sciences Purdue University Building 1338 Civil Engineering West Lafayette, IN 47906-1338 (Pharmacology, Toxicology, Chemical Metabolism) |
Susan Fischer, Ph.D. (6/00) Professor of Carcinogenesis The University of Texas M.D. Anderson Cancer Center Science Park - Research Division Box 116 P.O. Box 389 Smithville, TX 78957 (Experimental Carcinogenesis) |
| Clay Frederick, Ph.D. (6/00) Senior Research Fellow Mechanistic Toxicology Group Toxicology Rohm and Haas Company 727 Norristown Road Spring House, PA 19477 (Toxicology, Animal Models) |
George Friedman-Jimenez, M.D., DrPH. (6/98) Director, School of Public Health HHC/Bellevue Occupational & Env. Medicine Clinic Bellevue Hospital, Room CD349 462 First Avenue New York, NY 10016-9198 (Occupational Epidemiology, Environmental Justice) |
| Carol J. Henry, Ph.D. (6/97) Director Health and Environmental Science Department American Petroleum Institute 1220 L Street, NW Washington, DC 20005-4070 (Toxicology, Risk Assessment) |
Nicholas K. Hooper, Ph.D. (6/00) Head, Research & Methods Development Hazardous Materials Laboratory Department of Toxic Substances Control California Department of Health Services 2151 Berkeley Way, Annex 11 Berkeley, CA 94704 (Cancer, Genetic Hazard Assessment) |
| Franklin E. Mirer, Ph.D. (6/97) * Director Health and Safety Department UAW International 8000 East Jefferson Avenue Detroit, MI 48214-2699 (Toxicology, Occupational Health) |
John J. Mulvihill, M.D. (6/98) Professor of Human Genetics University of Pittsburgh Graduate School of Public Health A 302 Crabtree Hall Pittsburgh, PA 15261-0001 (Genetic Epidemiology) |
| Curtis Parker, Ph.D. (6/00) Professor and Chairman Department of Anatomy Morehouse School of Medicine 9720 Westview Drive Atlanta, GA 30310 (Developmental Biology) |
Richard E. Peterson, Ph.D. (6/99) Professor, Div of Pharmacology & Toxicology School of Pharmacy University of Wisconsin 425 North Charter Street Madison, WI 53706 (Reproductive & Developmental Toxicology) |
| Patricia M. Rodier, Ph.D. (6/00) Senior Scientist, Dept of OB/GYN, Box 668 University of Rochester Medical Center 601 Elmwood Avenue Rochester, NY 14642 (Developmental Neuroscience) |
John J. Stegeman, Ph.D. (6/97) (Chair) Senior Scientist Biology Department Woods Hole Oceanographic Institution Woods Hole, MA 02543 (Alternatives, Xenobiotic Metabolism) |
| Expert Consultants Hiroshi Yamasaki, Ph.D. (6/98) Chief, Unit of Multistage Carcinogenesis International Agency for Res on Cancer 150 Cours Albert-Thomas 69372 Lyon Cedex FRANCE (Experimental Carcinogenesis) |
Dr. William Farland Director Office of Health and Environmental Assessment (RD-689) Office of Research and Development U.S. Environmental Protection Agency Mail Drop 8601 401 M Street, S.W. Washington, D.C. 20460-0003 |
| Dr. Michael Lieberman Chairman, Department of Pathology Baylor College of Medicine Department of Pathology 1 Baylor Plaza Houston, TX 77030 |
Dr. James MacDonald Senior Vice President Drug Safety and Metabolism Schering-Plough Research Institute 2015 Galloping Hill Road Kenilworth, NJ 07033-0539 |
| Dr. Bernard Schwetz Director National Center for Toxicological Research Food and Drug Administration FDA HF-32 Room 17-35 Parklawn Building 5600 Fishers Lane Rockville, MD 20857 |
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