Publicly available data from the NCI Yeast Anticancer Drug Screen
Stage2 tested compounds that inhibit the growth of the rad18 mutant strain
The table below lists data for 123 compounds that inhibit the growth of the rad18 mutant strain by at least 70% at the dose indicated.
Compounds that inhibit only the rad18 mutant strain by at least 70% for at least one dose are at the top of the table.
Compounds that inhibit the rad18 mutant strain PLUS several other strains by at least 70% are listed further down in the table. Caution: rad18 is not necessarily the most sensitive strain when multiple strains are listed.
- Click on Stage2 Graphs to retrieve dose-response curves and a bar graph of the IC50 values from which the IC50 value of the appropriate wild type control has been subtracted.
- Click on 60 Cell Data to retrieve data (if available) from the 60 Human Tumor Cell Line Screen and to run COMPARE (an algorithm that finds compounds and molecular targets with similar patterns in the 60 cell screen). Not all compounds have been tested in the 60 cell line screen.
- To retrieve structural information (if any is available) click on 3D Structure.
- wt1 serves as the control for CLN2oe, bub3, mec2, rad14, rad18, rad50 & rad52.
- wt2 serves as the control for mgt1, mlh1, rad50EPP+ & sgs1.
Previous 300 compounds that inhibit rad18
Inhibited Strains
| NSC/name | 1.2 microM | 3.7 microM | 11 microM | 33 microM | 100 microM | Stage2 Graphs | NCI 60 Human Tumor Cell Data | 3D Structure of Compound | Basic Chemical Data |
|
659102
|
rad18 mgt1 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 659102 | 60 Cell Data for 659102 | 3D Structure for 659102 | Basic Chemical Data for 659102 | ||||
|
662455
|
rad18 rad50 | CLN2oe mec2 rad18 rad50 rad52 wt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad18 rad50 rad52 mlh1 sgs1 wt2 | Stage2 Graphs for 662455 | 60 Cell Data for 662455 | 3D Structure for 662455 | Basic Chemical Data for 662455 | ||
|
664150
BIS(2-CHLOROETHYL)-N-METHYL -N[(8-NITRO-1-NAPHTHYL)- METHYL]AMMONIUM CHLORIDE |
rad18 rad52 rad50EPP+ | rad14 rad18 rad50 rad52 rad50EPP+ | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 664150 | 60 Cell Data for 664150 | 3D Structure for 664150 | Basic Chemical Data for 664150 | ||
|
665125
|
rad18 rad52 wt2 | Stage2 Graphs for 665125 | 60 Cell Data for 665125 | 3D Structure for 665125 | Basic Chemical Data for 665125 | ||||
|
665278
|
rad14 rad18 | CLN2oe bub3 rad14 rad18 rad50 rad52 | Stage2 Graphs for 665278 | 60 Cell Data for 665278 | 3D Structure for 665278 | Basic Chemical Data for 665278 | |||
|
665626
|
rad18 rad50 rad50EPP+ | all | all | all | Stage2 Graphs for 665626 | 60 Cell Data for 665626 | 3D Structure for 665626 | Basic Chemical Data for 665626 | |
|
671176
|
rad18 rad50 rad52 | Stage2 Graphs for 671176 | 60 Cell Data for 671176 | 3D Structure for 671176 | Basic Chemical Data for 671176 | ||||
|
673145
|
rad18 rad50 rad52 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | all | Stage2 Graphs for 673145 | 60 Cell Data for 673145 | 3D Structure for 673145 | Basic Chemical Data for 673145 | ||
|
673146
|
rad50EPP+ | rad18 rad52 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 673146 | 60 Cell Data for 673146 | 3D Structure for 673146 | Basic Chemical Data for 673146 | |||
|
674212
|
rad18 rad50EPP+ | CLN2oe bub3 rad14 rad18 rad50 rad52 mgt1 rad50EPP+ sgs1 | CLN2oe bub3 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 674212 | 60 Cell Data for 674212 | 3D Structure for 674212 | Basic Chemical Data for 674212 | ||
|
674499
|
rad18 rad50 rad52 | Stage2 Graphs for 674499 | 60 Cell Data for 674499 | 3D Structure for 674499 | Basic Chemical Data for 674499 | ||||
|
675369
|
rad18 rad50 rad52 | Stage2 Graphs for 675369 | 60 Cell Data for 675369 | 3D Structure for 675369 | Basic Chemical Data for 675369 | ||||
|
680510
1,8-NAPHTHYRIDIN-3-AMINE, 2,7-DICHLORO-5-METHYL- |
rad14 rad18 mgt1 mlh1 wt2 | Stage2 Graphs for 680510 | 60 Cell Data for 680510 | 3D Structure for 680510 | Basic Chemical Data for 680510 | ||||
|
687370
|
rad18 rad50 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 687370 | 60 Cell Data for 687370 | 3D Structure for 687370 | Basic Chemical Data for 687370 | ||||
|
403546
|
bub3 | bub3 rad18 rad50 | bub3 rad18 rad50 rad50EPP+ | bub3 rad18 rad50 rad52 rad50EPP+ | bub3 rad18 rad50 rad52 mlh1 rad50EPP+ | Stage2 Graphs for 403546 | 60 Cell Data for 403546 | 3D Structure for 403546 | Basic Chemical Data for 403546 |
|
632
1,2-EPOXY-3-(1-NAPHTHYLOXY) PROPANE |
rad18 rad50EPP+ sgs1 | rad18 rad50 rad52 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 632 | 3D Structure for 632 | Basic Chemical Data for 632 | |||
|
142481
|
rad18 rad50 rad52 sgs1 | rad14 rad18 rad50 rad52 mgt1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 142481 | 60 Cell Data for 142481 | 3D Structure for 142481 | Basic Chemical Data for 142481 | ||
|
338423
|
rad18 rad52 rad50EPP+ sgs1 | rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 338423 | 3D Structure for 338423 | Basic Chemical Data for 338423 | ||||
|
683910
|
bub3 rad18 rad50 mgt1 sgs1 wt2 | bub3 rad18 rad50 mgt1 sgs1 wt2 | Stage2 Graphs for 683910 | 60 Cell Data for 683910 | 3D Structure for 683910 | Basic Chemical Data for 683910 | |||
|
1544
2-[(4-CHLOROBENZYLIDENE) AMINO]PHENOL |
bub3 | bub3 rad18 rad50 | Stage2 Graphs for 1544 | 3D Structure for 1544 | Basic Chemical Data for 1544 | ||||
|
4702
3-NITRO-9-NITROSOCARBAZOLE |
bub3 rad18 rad50 rad52 | all | Stage2 Graphs for 4702 | 60 Cell Data for 4702 | 3D Structure for 4702 | Basic Chemical Data for 4702 | |||
|
8922
ANTIBIOTIC C190-4 |
rad14 rad18 sgs1 | mec2 rad14 rad18 rad50 rad52 sgs1 | CLN2oe mec2 rad14 rad18 rad50 rad52 wt1 mgt1 sgs1 | all | CLN2oe bub3 mec2 rad14 rad18 rad50 mgt1 mlh1 rad50EPP+ | Stage2 Graphs for 8922 | Basic Chemical Data for 8922 | ||
|
19832
4-BIS(2-CHLOROETHYL)AMINO BENZALDEHYDE |
rad18 rad50 rad52 rad50EPP+ sgs1 | CLN2oe bub3 mec2 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 19832 | 60 Cell Data for 19832 | 3D Structure for 19832 | Basic Chemical Data for 19832 | |||
|
82892
NOGALAMYCIN COMPOUND B |
rad14 rad18 rad50 | all | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 82892 | 60 Cell Data for 82892 | 3D Structure for 82892 | Basic Chemical Data for 82892 | ||
|
90862
|
bub3 rad18 mgt1 | bub3 mec2 rad14 rad18 rad50 mgt1 | Stage2 Graphs for 90862 | 60 Cell Data for 90862 | 3D Structure for 90862 | Basic Chemical Data for 90862 | |||
|
100289
RUTILANTIN HYDROCHLORIDE |
rad50 rad52 | mec2 rad18 rad50 rad52 rad50EPP+ | all | Stage2 Graphs for 100289 | Basic Chemical Data for 100289 | ||||
|
113323
|
bub3 | bub3 rad18 sgs1 | Stage2 Graphs for 113323 | 3D Structure for 113323 | Basic Chemical Data for 113323 | ||||
|
114016
|
rad18 mlh1 rad50EPP+ | Stage2 Graphs for 114016 | 3D Structure for 114016 | Basic Chemical Data for 114016 | |||||
|
114574
FIGAROIC ACID |
rad14 rad18 rad50 rad52 | CLN2oe mec2 rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 | Stage2 Graphs for 114574 | Basic Chemical Data for 114574 | |||||
|
116758
|
rad18 rad50EPP+ sgs1 | CLN2oe mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 | Stage2 Graphs for 116758 | 3D Structure for 116758 | Basic Chemical Data for 116758 | ||||
|
123147
|
rad18 rad50 rad52 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 123147 | 3D Structure for 123147 | Basic Chemical Data for 123147 | |||
|
129585
|
rad50EPP+ | bub3 rad18 rad50 rad52 rad50EPP+ | bub3 rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 129585 | 3D Structure for 129585 | Basic Chemical Data for 129585 | |||
|
131734
|
rad14 rad18 rad52 sgs1 wt2 | bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 131734 | 60 Cell Data for 131734 | 3D Structure for 131734 | Basic Chemical Data for 131734 | |||
|
134662
|
rad18 mlh1 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 134662 | 3D Structure for 134662 | Basic Chemical Data for 134662 | ||||
|
135812
|
rad14 rad18 rad50 rad52 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 135812 | 60 Cell Data for 135812 | 3D Structure for 135812 | Basic Chemical Data for 135812 | |||
|
140399
|
rad18 mgt1 sgs1 | Stage2 Graphs for 140399 | 3D Structure for 140399 | Basic Chemical Data for 140399 | |||||
|
141562
|
rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 141562 | 60 Cell Data for 141562 | 3D Structure for 141562 | Basic Chemical Data for 141562 | ||||
|
158391
|
bub3 rad18 rad50 rad52 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 158391 | 60 Cell Data for 158391 | 3D Structure for 158391 | Basic Chemical Data for 158391 | |||
|
166291
|
bub3 rad18 rad50 | Stage2 Graphs for 166291 | 60 Cell Data for 166291 | 3D Structure for 166291 | Basic Chemical Data for 166291 | ||||
|
170669
|
rad50EPP+ | rad18 rad50 rad52 rad50EPP+ sgs1 | bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 170669 | 3D Structure for 170669 | Basic Chemical Data for 170669 | |||
|
201835
|
rad14 rad18 sgs1 | Stage2 Graphs for 201835 | 60 Cell Data for 201835 | 3D Structure for 201835 | Basic Chemical Data for 201835 | ||||
|
234714
APHIDICOLIN |
mec2 | mec2 rad18 rad52 | CLN2oe bub3 mec2 rad14 rad18 rad50 mgt1 mlh1 | Stage2 Graphs for 234714 | 60 Cell Data for 234714 | Basic Chemical Data for 234714 | |||
|
258613
TIN, (2,2'-BIPYRIDINE-N,N') DICHLORODIMETHYL- |
bub3 rad18 rad50 | all | Stage2 Graphs for 258613 | 60 Cell Data for 258613 | Basic Chemical Data for 258613 | ||||
|
278317
|
rad18 rad50 rad52 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | all | Stage2 Graphs for 278317 | 3D Structure for 278317 | Basic Chemical Data for 278317 | |||
|
296653
ZINC, CHLORO[2-(2-PYRIDINYL METHYLENE)HYDRAZINECARBO THIOAMIDATO-N(N(2)),N2,S]-, (T-4)- |
mec2 rad18 sgs1 | Stage2 Graphs for 296653 | Basic Chemical Data for 296653 | ||||||
|
297093
1,3-DIOXANE-4,6-DIONE, 2,2- DIMETHYL-5-[(5-NITRO-2-THIENYL) METHYLENE]- |
rad18 mgt1 rad50EPP+ | CLN2oe rad14 rad50 rad52 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 297093 | 60 Cell Data for 297093 | 3D Structure for 297093 | Basic Chemical Data for 297093 | |||
|
298509
|
bub3 | bub3 rad18 rad50 rad52 | Stage2 Graphs for 298509 | 3D Structure for 298509 | Basic Chemical Data for 298509 | ||||
|
308005
BENZ[CD]INDOLE-2-CARBOXYLIC ACID, 4-BROMO-1,3,4,5-TETRA HYDRO-5-OXO-, ETHYL ESTER |
wt2 | mec2 rad18 rad52 wt2 | bub3 mec2 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 308005 | 60 Cell Data for 308005 | 3D Structure for 308005 | Basic Chemical Data for 308005 | ||
|
309879
|
rad14 rad18 rad50 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 309879 | 60 Cell Data for 309879 | 3D Structure for 309879 | Basic Chemical Data for 309879 | ||
|
337851
PREDORINE |
rad18 rad50 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 | all | Stage2 Graphs for 337851 | 60 Cell Data for 337851 | 3D Structure for 337851 | Basic Chemical Data for 337851 | ||
|
380271
|
rad18 rad50 rad52 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 | all | Stage2 Graphs for 380271 | 60 Cell Data for 380271 | 3D Structure for 380271 | Basic Chemical Data for 380271 | ||
|
401158
2-ANTHRAQUINONE CARBOXALDEHYDE |
rad50 rad52 rad50EPP+ | rad18 rad50 rad52 mlh1 rad50EPP+ | Stage2 Graphs for 401158 | 3D Structure for 401158 | Basic Chemical Data for 401158 | ||||
|
401357
|
rad50EPP+ | rad18 rad50 rad52 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 | Stage2 Graphs for 401357 | 3D Structure for 401357 | Basic Chemical Data for 401357 | |||
|
401990
CHALCONE, ALPHA- (BROMOMETHYL)- |
rad18 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 401990 | 3D Structure for 401990 | Basic Chemical Data for 401990 | |||
|
402756
1-METHOXYPHENAZINE |
rad18 rad50 rad52 mgt1 rad50EPP+ | all | Stage2 Graphs for 402756 | 60 Cell Data for 402756 | 3D Structure for 402756 | Basic Chemical Data for 402756 | |||
|
403126
|
CLN2oe rad18 rad50 rad52 | Stage2 Graphs for 403126 | 3D Structure for 403126 | Basic Chemical Data for 403126 | |||||
|
404917
|
rad18 rad50 rad52 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 404917 | 3D Structure for 404917 | Basic Chemical Data for 404917 | ||
|
405903
|
rad18 rad50EPP+ sgs1 | all | all | all | Stage2 Graphs for 405903 | 3D Structure for 405903 | Basic Chemical Data for 405903 | ||
|
406433
|
rad18 rad50 rad52 sgs1 | all | all | all | Stage2 Graphs for 406433 | 60 Cell Data for 406433 | 3D Structure for 406433 | Basic Chemical Data for 406433 | |
|
407008
|
bub3 rad14 rad18 | bub3 mec2 rad14 rad18 rad50 rad52 mlh1 sgs1 | bub3 mec2 rad14 rad18 rad50 rad52 mlh1 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 407008 | 60 Cell Data for 407008 | 3D Structure for 407008 | Basic Chemical Data for 407008 |
|
408003
|
bub3 rad18 rad50EPP+ | all | all | Stage2 Graphs for 408003 | 3D Structure for 408003 | Basic Chemical Data for 408003 | |||
|
525118
|
rad18 rad50 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 525118 | 60 Cell Data for 525118 | 3D Structure for 525118 | Basic Chemical Data for 525118 | ||
|
529861
ASPARTIC ACID, N-[P-[[(2,4- DIAMINO-5-CHLORO-6-QUINAZOLINYL) METHYL]AMINO]BENZOYL]-, L |
mec2 | mec2 rad18 rad52 | bub3 mec2 rad14 rad18 rad50 rad52 wt1 | Stage2 Graphs for 529861 | 3D Structure for 529861 | Basic Chemical Data for 529861 | |||
|
602889
|
bub3 rad18 rad50EPP+ | Stage2 Graphs for 602889 | 60 Cell Data for 602889 | 3D Structure for 602889 | Basic Chemical Data for 602889 | ||||
|
607301
L-GLUTAMIC ACID, N-[4-[[(2,4- DIAMINO-6-PTERIDINYL) METHYL] AMINO]-3-FLUOROBENZOYL]-, TRIFLUOROACETATE |
mec2 | mec2 rad18 rad52 | bub3 mec2 rad14 rad18 rad50 rad52 wt1 | Stage2 Graphs for 607301 | 60 Cell Data for 607301 | 3D Structure for 607301 | Basic Chemical Data for 607301 | ||
|
607740
|
rad50EPP+ | rad18 rad50 rad50EPP+ sgs1 | rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 | all | Stage2 Graphs for 607740 | 60 Cell Data for 607740 | 3D Structure for 607740 | Basic Chemical Data for 607740 |
|
608340
|
rad14 rad18 sgs1 | Stage2 Graphs for 608340 | 3D Structure for 608340 | Basic Chemical Data for 608340 | |||||
|
613038
|
rad18 rad52 sgs1 | Stage2 Graphs for 613038 | 3D Structure for 613038 | Basic Chemical Data for 613038 | |||||
|
614925
|
bub3 rad18 rad50 | Stage2 Graphs for 614925 | 60 Cell Data for 614925 | 3D Structure for 614925 | Basic Chemical Data for 614925 | ||||
|
621482
|
rad18 rad52 sgs1 | rad18 rad50 rad52 mlh1 sgs1 wt2 | mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | Stage2 Graphs for 621482 | 60 Cell Data for 621482 | 3D Structure for 621482 | Basic Chemical Data for 621482 |
|
634567
|
rad50 | rad50 rad52 | rad18 rad50 rad52 sgs1 | Stage2 Graphs for 634567 | 60 Cell Data for 634567 | 3D Structure for 634567 | Basic Chemical Data for 634567 | ||
|
637660
|
rad18 rad50 rad52 rad50EPP+ sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | all | Stage2 Graphs for 637660 | 60 Cell Data for 637660 | 3D Structure for 637660 | Basic Chemical Data for 637660 | ||
|
638156
MALONIC ACID, P-PHENYL BENZYLIDENE- |
bub3 rad18 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 638156 | 60 Cell Data for 638156 | 3D Structure for 638156 | Basic Chemical Data for 638156 | |||
|
645622
|
bub3 rad18 rad50 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 645622 | 60 Cell Data for 645622 | 3D Structure for 645622 | Basic Chemical Data for 645622 | |||
|
653551
|
rad18 rad52 sgs1 | CLN2oe bub3 mec2 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 653551 | 60 Cell Data for 653551 | 3D Structure for 653551 | Basic Chemical Data for 653551 | |||
|
658913
|
rad18 rad50 sgs1 | Stage2 Graphs for 658913 | 60 Cell Data for 658913 | 3D Structure for 658913 | Basic Chemical Data for 658913 | ||||
|
663650
|
rad14 rad18 rad50 rad52 | all | Stage2 Graphs for 663650 | 60 Cell Data for 663650 | 3D Structure for 663650 | Basic Chemical Data for 663650 | |||
|
666398
|
CLN2oe rad18 rad50 rad52 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 sgs1 wt2 | CLN2oe mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 666398 | 60 Cell Data for 666398 | 3D Structure for 666398 | Basic Chemical Data for 666398 | ||
|
669160
1-AZIDO-2-(2-PYRIDYL)- PHENALEN-3-ONE |
rad50EPP+ | CLN2oe rad18 rad50 rad52 rad50EPP+ | Stage2 Graphs for 669160 | 60 Cell Data for 669160 | 3D Structure for 669160 | Basic Chemical Data for 669160 | |||
|
669735
|
bub3 rad14 rad18 | CLN2oe bub3 rad14 rad18 rad52 mgt1 sgs1 wt2 | CLN2oe bub3 rad14 rad18 rad52 mgt1 sgs1 wt2 | Stage2 Graphs for 669735 | 60 Cell Data for 669735 | 3D Structure for 669735 | Basic Chemical Data for 669735 | ||
|
669965
|
rad50 rad52 rad50EPP+ | rad50 rad52 rad50EPP+ | rad50 rad52 rad50EPP+ | rad50 rad52 rad50EPP+ | CLN2oe rad18 rad50 rad52 rad50EPP+ | Stage2 Graphs for 669965 | 60 Cell Data for 669965 | 3D Structure for 669965 | Basic Chemical Data for 669965 |
|
670701
|
rad14 rad18 sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 670701 | 60 Cell Data for 670701 | 3D Structure for 670701 | Basic Chemical Data for 670701 |
|
674088
|
rad14 rad18 rad50 | all | Stage2 Graphs for 674088 | 60 Cell Data for 674088 | 3D Structure for 674088 | Basic Chemical Data for 674088 | |||
|
740
METHOTREXATE |
mec2 | mec2 rad14 rad18 rad50 rad52 | Stage2 Graphs for 740 | 60 Cell Data for 740 | 3D Structure for 740 | Basic Chemical Data for 740 | |||
|
15265
|
bub3 rad18 rad50 sgs1 | bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 15265 | 3D Structure for 15265 | Basic Chemical Data for 15265 | ||||
|
76919
2-PYRIDINECARBOXYLIC ACID, 5-AMINO-6-(7-AMINO-1,2,3,4,5,8- HEXAHYDRO- 5,8-DIOXO-2- QUINOLINYL)-4-(2-HYDROXY- 3,4- DIMETHOXYPHENYL)-3-METHYL- |
mec2 rad14 rad18 rad50 rad52 | mec2 rad14 rad18 rad50 rad52 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 76919 | 60 Cell Data for 76919 | 3D Structure for 76919 | Basic Chemical Data for 76919 |
|
78572
4-HYDROXYAMINOQUINOLINE 1-OXIDE HYDROCHLORIDE |
rad14 rad18 rad50 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 | Stage2 Graphs for 78572 | 60 Cell Data for 78572 | 3D Structure for 78572 | Basic Chemical Data for 78572 |
|
82493
2-PROPANONE, 1,3- DIMERCAPTO-, SEMICARBAZONE |
rad14 rad18 rad50 rad52 sgs1 | Stage2 Graphs for 82493 | 60 Cell Data for 82493 | 3D Structure for 82493 | Basic Chemical Data for 82493 | ||||
|
86005
COMPOUND A FROM NOGALAMYCIN |
rad14 rad18 rad50 mlh1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 86005 | 60 Cell Data for 86005 | 3D Structure for 86005 | Basic Chemical Data for 86005 | ||
|
116413
|
bub3 rad18 mlh1 sgs1 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 116413 | 3D Structure for 116413 | Basic Chemical Data for 116413 | ||||
|
117196
|
bub3 rad18 rad52 sgs1 | all | all | all | Stage2 Graphs for 117196 | 60 Cell Data for 117196 | 3D Structure for 117196 | Basic Chemical Data for 117196 | |
|
125066
BLEOMYCIN SULFATE |
rad14 rad18 rad50 rad52 sgs1 | all | Stage2 Graphs for 125066 | 60 Cell Data for 125066 | Basic Chemical Data for 125066 | ||||
|
129957
|
bub3 rad50EPP+ | bub3 mec2 rad18 rad50EPP+ | bub3 mec2 rad14 rad18 mgt1 rad50EPP+ | Stage2 Graphs for 129957 | 3D Structure for 129957 | Basic Chemical Data for 129957 | |||
|
132666
|
rad50EPP+ | rad50 rad52 rad50EPP+ | mec2 rad50 rad52 rad50EPP+ | mec2 rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 132666 | 3D Structure for 132666 | Basic Chemical Data for 132666 | ||
|
137044
|
rad50EPP+ | bub3 rad18 rad52 mgt1 rad50EPP+ | Stage2 Graphs for 137044 | 3D Structure for 137044 | Basic Chemical Data for 137044 | ||||
|
140373
|
rad50EPP+ | bub3 rad18 rad50 rad52 rad50EPP+ sgs1 | all | Stage2 Graphs for 140373 | 3D Structure for 140373 | Basic Chemical Data for 140373 | |||
|
173908
1-NAPHTHALENEPROPANOL, ALPHA-ETHENYLDECAHYDRO-3- HYDROXY-ALPHA,5,5,8A-TETRA METHYL-2-METHYLENE- (9 |
rad14 rad18 rad50 rad52 sgs1 | Stage2 Graphs for 173908 | 60 Cell Data for 173908 | 3D Structure for 173908 | Basic Chemical Data for 173908 | ||||
|
191250
|
rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 | Stage2 Graphs for 191250 | 3D Structure for 191250 | Basic Chemical Data for 191250 | |||||
|
228132
BENZOFURAZAN, 5-NITRO-6- (1-PIPERIDINYL)-, 1-OXIDE |
mec2 rad18 rad50EPP+ sgs1 wt2 | all | all | all | Stage2 Graphs for 228132 | 60 Cell Data for 228132 | 3D Structure for 228132 | Basic Chemical Data for 228132 | |
|
249008
TRIMETREXATE |
mec2 | mec2 rad18 rad50 sgs1 | Stage2 Graphs for 249008 | 3D Structure for 249008 | Basic Chemical Data for 249008 | ||||
|
251219
5-AMINO-1-METHYL-1H-IMID AZOLE-4-CARBOSELENOAMIDE |
rad52 rad50EPP+ | bub3 mec2 rad50 rad52 rad50EPP+ | bub3 mec2 rad18 rad50 rad52 rad50EPP+ | bub3 rad18 rad50 rad52 rad50EPP+ | Stage2 Graphs for 251219 | 3D Structure for 251219 | Basic Chemical Data for 251219 | ||
|
313670
|
bub3 mec2 rad18 sgs1 | Stage2 Graphs for 313670 | 3D Structure for 313670 | Basic Chemical Data for 313670 | |||||
|
319662
|
rad50EPP+ | rad50EPP+ | bub3 mec2 rad18 rad52 rad50EPP+ | all | Stage2 Graphs for 319662 | 3D Structure for 319662 | Basic Chemical Data for 319662 | ||
|
328201
|
rad14 rad18 rad50 rad52 sgs1 | all | Stage2 Graphs for 328201 | 60 Cell Data for 328201 | Basic Chemical Data for 328201 | ||||
|
329226
|
rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | Stage2 Graphs for 329226 | 60 Cell Data for 329226 | 3D Structure for 329226 | Basic Chemical Data for 329226 |
|
351239
BENZENE, 1,4-DICHLORO-2,5- BIS(2-NITROETHENYL)- |
bub3 rad14 rad18 rad50 rad52 | bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 | Stage2 Graphs for 351239 | 60 Cell Data for 351239 | 3D Structure for 351239 | Basic Chemical Data for 351239 | ||
|
371189
|
bub3 rad18 mgt1 rad50EPP+ | bub3 mec2 rad14 rad18 rad50 mgt1 mlh1 rad50EPP+ | Stage2 Graphs for 371189 | 60 Cell Data for 371189 | Basic Chemical Data for 371189 | ||||
|
380725
PYRROLO[2,1-B]THIAZOLE-6,7- DIMETHANOL, 5-(3,4-DICHLORO PHENYL)-, BIS(METHYL CARBAMATE) (ESTER) |
rad14 rad18 rad50 rad52 sgs1 | Stage2 Graphs for 380725 | 60 Cell Data for 380725 | 3D Structure for 380725 | Basic Chemical Data for 380725 | ||||
|
400541
|
rad14 rad18 rad50 rad50EPP+ sgs1 | all | Stage2 Graphs for 400541 | 3D Structure for 400541 | Basic Chemical Data for 400541 | ||||
|
400594
|
rad50EPP+ | rad50EPP+ | rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 | Stage2 Graphs for 400594 | Basic Chemical Data for 400594 | ||||
|
401166
|
bub3 rad18 rad50 mgt1 | bub3 rad18 rad50 rad52 mgt1 mlh1 sgs1 | Stage2 Graphs for 401166 | 60 Cell Data for 401166 | 3D Structure for 401166 | Basic Chemical Data for 401166 | |||
|
403805
|
rad50EPP+ | bub3 rad18 rad50 rad52 rad50EPP+ sgs1 | all | Stage2 Graphs for 403805 | 60 Cell Data for 403805 | 3D Structure for 403805 | Basic Chemical Data for 403805 | ||
|
611360
PREPACIFENNOL EPOXIDE |
rad18 rad50 mgt1 sgs1 | all | Stage2 Graphs for 611360 | 3D Structure for 611360 | Basic Chemical Data for 611360 | ||||
|
616357
|
rad14 rad18 rad50 rad52 sgs1 | Stage2 Graphs for 616357 | 60 Cell Data for 616357 | 3D Structure for 616357 | Basic Chemical Data for 616357 | ||||
|
617988
DIBENZO[A,C]PHENAZINE-10- CARBOXAMIDE, N-[2- (DIMETHYL AMINO)ETHYL]-, MONOHYDROCHLORIDE |
bub3 rad18 rad50 rad52 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 617988 | 60 Cell Data for 617988 | 3D Structure for 617988 | Basic Chemical Data for 617988 | ||
|
630510
N-METHYLTAMOXIFEN IODIDE |
rad14 rad18 rad50 mlh1 | all | all | all | Stage2 Graphs for 630510 | 60 Cell Data for 630510 | 3D Structure for 630510 | Basic Chemical Data for 630510 | |
|
642938
|
bub3 | bub3 rad18 rad52 sgs1 | Stage2 Graphs for 642938 | 60 Cell Data for 642938 | 3D Structure for 642938 | Basic Chemical Data for 642938 | |||
|
652888
|
rad14 rad18 rad52 sgs1 | rad14 rad18 rad50 rad52 sgs1 | mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 | all | all | Stage2 Graphs for 652888 | 60 Cell Data for 652888 | 3D Structure for 652888 | Basic Chemical Data for 652888 |
|
658139
9H-FLUOREN-9-ONE, 2,4,7-TRI NITRO-, (9,10-DIHYDROANTHRACEN - 9-YLIDENE)HYDRAZONE |
mec2 rad18 mgt1 rad50EPP+ | all | all | all | Stage2 Graphs for 658139 | 60 Cell Data for 658139 | 3D Structure for 658139 | Basic Chemical Data for 658139 | |
|
661224
|
rad50EPP+ | rad18 mgt1 mlh1 rad50EPP+ | Stage2 Graphs for 661224 | 60 Cell Data for 661224 | 3D Structure for 661224 | Basic Chemical Data for 661224 | |||
|
666736
|
rad14 rad18 rad50 sgs1 | mec2 rad14 rad18 rad50 rad52 sgs1 | CLN2oe mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 | all | all | Stage2 Graphs for 666736 | 60 Cell Data for 666736 | 3D Structure for 666736 | Basic Chemical Data for 666736 |
|
668370
3,3-DIIODO-2-PHENYL-2-PROPENAL |
rad50 rad52 rad50EPP+ | rad50 rad52 rad50EPP+ | rad14 rad18 rad50 rad52 mgt1 rad50EPP+ | all | all | Stage2 Graphs for 668370 | 60 Cell Data for 668370 | 3D Structure for 668370 | Basic Chemical Data for 668370 |
|
668840
|
CLN2oe mec2 rad18 rad50 rad52 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 | Stage2 Graphs for 668840 | 60 Cell Data for 668840 | 3D Structure for 668840 | Basic Chemical Data for 668840 |
Previous 300 compounds that inhibit rad18
Email questions to: Susan Holbeck [holbecks@mail.nih.gov]