Myocardial Ischemia and Metabolism [MIM]

[MIM Membership Roster] [MIM Meeting Rosters]


The Myocardial Ischemia and Metabolism [MIM] Study Section reviews applications involving basic and applied aspects of myocardial ischemia/reperfusion, coronary circulation, and myocardial metabolism. It includes the review of studies using molecular, genetic, cellular, biochemical, pharmacological, genomic, proteomic, and physiological approaches to define normal and pathological processes. MIM examines investigations at all levels of organization, ranging from in vitro models of simulated ischemia in isolated cells to whole animal models. Specific areas covered by MIM:

  • Mechanisms of ischemia/reperfusion tissue injury, myocardial stunning, infarction, and hibernation.
  • Cardioprotection, cardiac repair and regeneration including stem cell therapy.
  • Control of coronary blood flow in health and disease; post-ischemic coronary vascular abnormalities; development of collateral circulation in response to myocardial ischemia.
  • Signal transduction mechanisms of myocardial ischemia/reperfusion injury, preconditioning, and inflammation, including changes in receptor function, kinase activity, and transcription factor activity.
  • Role of reactive oxygen species, nitric oxide and other reactive nitrogen species, cytokines, chemokines, and white blood cells in myocardial ischemia/reperfusion injury.
  • Metabolism and energetics in normal myocardium and in acquired heart disease: carbohydrate and lipid metabolism, glycolysis, oxidative phosphorylation, substrate interaction, regulation of substrate transport and fluxes, and mitochondrial function.

Study Sections with most closely related areas of similar science listed in rank order are:

Cardiac Contractility, Hypertrophy, and Function [CCHF]
Clinical and Integrative Cardiovascular Sciences [CICS]
Bioengineering, Technology and Surgical Sciences [BTSS]
Cellular Mechanisms of Aging and Development [CMAD]

 

 



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