Vascular Cell and Molecular Biology Study Section [VCMB]

[VCMB Membership Roster] [VCMB Meeting Rosters]

The Vascular Cell and Molecular Biology [VCMB] Study Section reviews applications involving the cell and molecular biology of blood vessels ranging from major arteries to the microcirculation.  Studies using cellular, biochemical, biophysical, immunological, genetic, pharmacological, and molecular biological approaches to define vascular homeostasis and dysfunction are reviewed. A principal focus is on the biology of the endothelium, vascular smooth muscle cell, as well as adventitial cells and pericytes.

 

  • Vascular cell growth control; apoptosis, signaling pathways, intercellular communication.
  • Transcription and posttranscriptional related to vascular biology.  
  • Vasomotor activity, including vasocontraction and relaxation, leukocyte trafficking, adhesion molecules; chemokines, cytokines; intercellular signaling; reactive oxygen and nitrogen species; Endothelial barrier function; extracellular matrix-mediated signaling.
  • Injury/repair and associated angiogenesis and postnatal angiogenesis; remodeling; angioplasty; restenosis; grafts; stents; re-endothelialization; stem cells.
  • Mechanotransduction at the cellular level: hemodynamic forces; stress/strain; force transmission coupling in cells; mechanosignaling.
  • Protein biochemistry and structure biology of the vascular cells; proteomics; cellular dynamics through 3-D imaging; cytoskeleton; vesicular traffic.
  • Vascular contribution and response to coagulation: thrombosis and fibrinolysis mechanisms mediated by the vascular cells; platelet-endothelial interactions.

Study sections with most closely related areas of similar science listed in rank order are:

Hypertension and Microcirculation Study Section [HM] 
Atherosclerosis and Inflammation of the Cardiovascular System [AICS] 
Cardiovascular Differentiation and Development [CDD] 
Electrical Signaling, Ion Transport, and Arrhythmias [ESTA] 



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