Mission Statement:    

• Conducts studies aimed at determining the cellular and molecular mechanisms involved in synaptic transmission;    
• Examines effect of alcohol and other drugs of abuse on synaptic transmission; and   
• Determines the molecular mechanisms underlying these effects.

Staff:

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Gerdeman, G. and Lovinger, D.M. Postsynaptic endocannabinoid release is necessary for long-term depression in the striatum. Nature Neuroscience 2002;5:446-451.

Lovinger DM. NMDA receptors lose their inhibitions. Nat Neurosci 2002;5:614-6.  

Partridge, J. and Lovinger, D.M. Nicotinic Acetylcholine Receptors Interact with Dopamine in Induction of Striatal Long-Term Depression. J Neurosci 2002;22:2541-2549.

Stocca, G. and Lovinger, D.M. PKC and adenosine modulation of presynaptic calcium transients at hippocampal synapses Hippocampus 2002, in press.

Woo, N.-S., Delpire, E., Lue, J., England, R., McClellan, R., Dufour, S., Deutch, A.Y. and Lovinger, D.M. Hyper-excitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus 2002;12:258-268.

Lovinger DM, Sung KW, Zhou Q. Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells. Neuropharmacology 2000;39:561-70.    pdf

Lovinger DM. 5-HT3 receptors and the neural actions of alcohols: an increasingly exciting topic. Neurochem Int 1999;35:125-30. Review.    pdf

Alcohol publications can also be found using  ETOH Database