Summaries of Independent Scientist (K) Awards

Guise, Jeanne-Marie

Institution: Oregon Health Sciences University
Grant Title: Evidence-Based Decision Aids to Improve Women's Health
Grant Number: K08 HS011338
Duration: 5 years (2000-2005)
Total Award: $631,500

Project Description: The purpose of this research is to develop an evidence-based childbirth decision support tool to weigh the consequences for various childbirth methods, and test its effectiveness to improve patients' shared-decisionmaking and satisfaction, and reduce feelings of failure, anxiety and postpartum depression. This Web-based tool will be widely accessible, providing an opportunity to overcome the economic, racial, linguistic, and ethnic disparities that currently exist in prenatal education and health outcomes.

Career Goals: Dr. Guise is Associate Professor in the Department of Obstetrics and Gynecology (OB/GYN) at Oregon Health and Science University. She plans to become an independent physician-scientist researcher and mentor in academic OB/GYN. In addition, she would like to become an expert in translating research findings into practical tools for use by practitioners, patients, and policymakers; and plans on formal coursework in decision sciences and medical informatics to augment her skills in clinical epidemiology, medical ethics, biostatistics, and secondary analysis. Her long-term goal is to set a foundation for academic leadership in the integration of health services research into clinical and academic OB/GYN.

Progress to Date: Dr. Guise completed the Agency for Healthcare Research and Quality (AHRQ) funded evidence report of Vaginal Birth after Cesarean, which has resulted in the submission of seven manuscripts. She also developed a survey to assess patient satisfaction with the information they receive and priorities in decisionmaking for all women with prior cesarean delivery. Dr. Guise is mentoring others.

Future Plans: Dr. Guise will continue her work in bringing the best evidence to patients and providers for clinical decisionmaking. She is also continuing to pursue epidemiological, informatics, and clinical research to improve the health and safety of women and children in childbirth.

Highlights and Specific Accomplishments:

• Professional Memberships:
  • American Medical Association.
  • American College of Obstetricians and Gynecologists, Fellow.
• AHRQ Study Section Reviewer, Center for Outcomes and Evidence (COE).
• AHRQ Study Section Member, Healthcare Research Training (HRT).
• AHRQ Study Section Reviewer, Health Care Quality and Effectiveness Research (HCQER).

K-Generated Publications:

• Guise JM, Austin D, Morris C. Breastfeeding and Reduced Risk of Childhood Leukemia: An Evidence Review. Pediatrics (in press).
• Guise JM, Hashima JN, Osterweil P. Evidence-based VBAC. Best Practice and Research. Clinical Obstetrics and Gynaecology 2005;19(1):117-30.
• McDonagh MS, Osterweil P, Guise JM, The Benefits and Risks of Inducing Labour in Patients with Prior Caesarean Delivery: A Systematic Evidence Review. Biology 2005;112(9) (online early, hard copy in press).
• Dodd JM, Crowther CA, Huertas E, Guise JM, Horey D. Planned Elective Repeat Caesarean versus Planned Vaginal Birth for Women with a Previous Caesarean Birth. Cochrane Database of Systematic Reviews, Issue 4, 2004.
• Ghetti C, Chan B, Guise JM. Physicians' Responses to Patient Requested Cesarean. Birth 2004;31(4):280-4.
• Guise JM. Vaginal Birth After Caesarean: Determining Thresholds for Risks Requires Examining more than Uterine Rupture Rates. BMJ 2004;329(7462):375-6.
• Palda V, Guise JM, Wathen CM. Interventions to promote breastfeeding: applying the evidence in clinical practice. Canadian Medical Association Journal 2004;170(6):976-8.
• Kraemer DF, Berlin M, Guise JM. The Relationship of Health Care Delivery System Characteristics and Legal Factors to Mode of Delivery in Women with Prior Cesarean Section: A Systematic Review. Womens Health Issues 2004;14(3):94-103.
• Hashima JN, Eden KB, Nygren P, Osterweil P, Guise JM. Predicting Vaginal Birth After Cesarean: A Review of Prognostic Factors and Screening Tools. American Journal of Obstetrics and Gynecology 2004;190(2):547-55.
• Guise JM, Berlin M, McDonough M, et al. Safety of Vaginal Birth After Cesarean: A Systematic Review. Obstetrics and Gynecology 2004;103(3):420-9.
• Eden KB, Hashima JN, Osterweil P, Nygren P, Guise JM. Childbirth preferences after cesarean. Birth 2004;31(1):50-62.
• Guise JM, McDonagh M, Osterweil P, et al. Systematic Review of the Incidence and Consequences of Uterine Rupture in Women with Prior Cesarean Delivery. BMJ 2004;329(7456):19-23.
• Guise JM, Palada V, Westhoff C, Lieu A. The Effectiveness of Primary Care Based Interventions to Promote Breastfeeding: Systematic Evidence Review and Meta-analysis for the U.S. Preventive Services Task Force. Annals of Family Medicine 2003;1(2):70-80.
• Klebanoff MA, Guise JM, Carey JC. Treatment Recommendations for Bacterial Vaginosis in Pregnant Women [letter]. Clinical Infectious Disease 2003;36:1630-1.

AHRQ Research Portfolio: Informatics; Care Management; Training.
AHRQ Goals: Effectiveness

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