Washington University School of Medicine Digestive Disease Research Core Center : NIDDK

Washington University School of Medicine Digestive Disease Research Core Center

Washington University School of Medicine

Director: Ellen Li, M.D., Ph.D.
Co-directors: Nicholas Davidson, M.D., Jeffrey Gordon, M.D., Phillip Tarr, M.D
Administrator: Sandra Doyle

Center Focus

The University of Washington Digestive Disease Research Core Center (DDRC) focuses on regulatory factors in the gut. The concept of a DDRCC emerged from the collaborative and synergistic interactions of a large number of investigators engaged in digestive-diseases related research and include 43 principal investigators in the clinical and basic science departments of the Washington University School of Medicine as full members. The goals of the center are to (1) formalize and provide mechanisms for expanding the extensive collaborative and synergistic interactions already in place between a large number of independently funded investigators engaged in digestive diseases-related research; (2) pool department and divisional resources to provide services and expertise that might not otherwise be available to individual investigators, in a cost-effective manner; and (3) provide funding support for investigators to develop new digestive diseases-related research initiatives that will subsequently be competitive for more conventional mechanisms of funding. The four cores are designed to facilitate analysis of the regulatory factors in the GI tract both in vivo and in vitro and to correlate structure with function. The Administrative Core oversees the operation of the DDRCC and administers the Pilot and Feasibility Program to foster participation by younger, and established, investigators in digestive diseases-related research. In addition, the NIH-sponsored General Clinical Research Center at Washington University provides DDRC members with resources for conducting clinical research. Several DDRC members who are experts in translational GI research are utilizing the GCRC.

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Core Facilities

  • Transgenic Mouse/Stem Cell
  • Morphology
  • Protein Structure and Macromolecular Graphics
  • Genomics

Page last updated: April 07, 2008

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