November 7 – 8, 2005
Hyatt Regency Hotel, Bethesda, MD
AGENDA
The purpose and goals of the meeting are to: i) establish an ongoing dialogue among the various stakeholders (e.g., NIH, Academia, Industry, FDA and other Federal Agencies), ii) identify specific areas ripe for synergy and collaboration, and iii) facilitate the translation of discovery science supported by the NIDCR to products that will advance craniofacial health. The immediate goal of this first meeting will be to educate each of the stakeholders and demonstrate the value of industry’s participation in cross-disciplinary and multidisciplinary science projects.
November 7: From Discovery Science to Product Development
8:45–9:00 a.m. Welcome and Meeting Overview
Eleni Kousvelari, Acting Director
Center for Biotechnology and Innovation, NIDCR
9:00–9:30 a.m. The Challenge of Translational Research at the NIDCR
Lawrence Tabak, Director
NIDCR
9:30–10:15 a.m. Creating a Culture to Speed Discovery Science Toward Product Development
Ihor Rak, Executive Director
Emerging CNS Compounds, AstraZeneca
10:15–10:45 a.m. Break and Poster Viewing
Showcase of cutting-edge research and development by meeting participants
10:45–12:15 p.m. Beginning at the Beginning—NIDCR-Sponsored Research
Ann Sandberg, Acting Director
Center for Integrative Craniofacial Research, NIDCR
Sangeeta Bhargava, Program Director
Center for Infectious Diseases and Immunology, NIDCR
Eleni Kousvelari, Acting Director
Center for Biotechnology and Innovation, NIDCR
Bruce Pihlstrom, Acting Director
Center for Clinical Research, NIDCR
Dushanka Kleinman, Acting Director
Center for Health Promotion and Behavioral Research, NIDCR
Robert Angerer, Director
Division of Intramural Research, NIDCR
Highlights of NIDCR-supported research and future directions in the extramural and intramural programs.
12:15–12:30 p.m. Questions and Open Discussion
12:30–1:40 p.m. Lunch
1:45–2:30 p.m. Complexities of Developing New Diagnostics and Therapeutics:
From Bench Prototype to Commercial Reality
Christine Copple, Chief Executive Officer
American Society for Microbiology Resources
2:30–3:15 p.m. Using the Regulatory Approval Process to Facilitate/Drive Commercialization
Celia Witten, Director
Office of Cellular, Tissue, and Gene Therapies, Center for Biologics Evaluation and Research
U.S. Food and Drug Administration
3:15–3:45 p.m. Break and Poster Viewing
3:45–4:15 p.m. Funding Partnerships at NIDCR and NIH
Jo Anne Goodnight, Acting Director
Office of Extramural Programs, Office of Extramural Research, NIH
What is available, what is practical, and how to best position your team to leverage the broadest resource pool to further R&D
4:15–4:30 p.m. Imaging Technologies for Early Caries Detection: An Emerging Technology Transfer Success Story
George Stookey, Chief Executive Officer
Therametric Technologies, Inc. and
Professor Emeritus, Indiana University School of Dentistry
4:30–5:00 p.m. Facilitating Public-Private Partnerships
Barbara Mittleman, Acting Director
Office of Public-Private Partnerships
Office of the Director, NIH
5:00–5:15 p.m. EMERGING OPPORTUNITIES
R&D in DIAGNOSTICS AND PROTEOMICS
Industrial Perspective
Paul Billings, Vice President
Biotechnology and Health Care Strategy
Laboratory Corporation of America
5:30–7:00 p.m. Poster Viewing and Social Hour
November 8: Beyond Development to Practical Product
8:00–8:45 a.m. Continental Breakfast and Poster Viewing
8:45–10:00 a.m. EMERGING OPPORTUNITIES (continued)
R&D in DENTAL MATERIALS
Academic Perspective
Antoni Tomsia, Senior Staff Scientist, Materials Science
Lawrence Berkeley National Laboratory
Industry Perspective
Joseph Lichtenhan, Chief Executive Officer
Hybrid Plastics
SALIVARY DIAGNOSTICS AND PROTEOME
Academic Perspective
John Yates, Professor, Department of Cell Biology
Scripps Research Institute
INFLAMMATION/IMMUNOLOGY OF THE ORAL MUCOSA
Academic Perspective
Mark Herzberg, Professor
University of Minnesota School of Dentistry and NIDCR Advisory Council
Industrial Perspective
William Warren, Chief Executive Officer
VaxDesign, Inc.
10:00–10:15 a.m. Questions and Open Discussion
10:15–10:45 a.m. Break and Poster Viewing
EMERGING OPPORTUNITIES (continued)
10:45 –12:15 p.m. NEUROLOGY and OROFACIAL PAIN
Academic Perspective
Michael Iadarola, Chief
Integrative Neurobiology and Neuronal Gene Expression, NIDCR
Industrial Perspective
Franz Hefti, Executive Vice President for Drug Development
Rinat Neuroscience, Inc.
BIOENGINEERING OF ORAL, DENTAL AND CRANIOFACIAL TISSUES
Academic Perspective
Phillip Messersmith, Professor of Materials Science and Engineering
Northwestern University
Industrial Perspective
Anthony Ratcliffe, Chief Executive Officer, Synthasome, Inc.
WOUND HEALING
Academic Perspective
D. Roselyn Cerutis, Assistant Professor of Oral Biology
Creighton University School of Dentistry
Industrial Perspective
Alan Rudolph, Chief Executive Officer
Adlyfe, Inc.
12:15–12:30 p.m. Questions and Open Discussion
12:30–1:40 p.m. Lunch
1:45–2:15 p.m. Technology Transfer for Advancing Dentistry
Frederick Eichmiller, Director
Paffenbarger Research Center
American Dental Association and National Institute of Standards and Technology
2:15–2:45 p.m. From R&D to Market in the Cost-Conscious World of Dental Products
Donna Janson, Chief Executive Officer
Novalar Pharmaceuticals
2:45–3:15 p.m. Break and Poster Viewing
3:15–4:00 p.m. The New Genetics in Transitioning from Treatment to Prevention in Oral Health Care
Marcia Lewis, Senior Director for Oncology
Celera Diagnostics
4:00–5:00 p.m. Improving Translations in Orofacial Health Research—Reaction and Panel Discussion
Moderator
Michael Barnett, Interim Associate Dean for Research
New Jersey Dental School
Panelists
Jeremy Mao, Associate Professor
University of Illinois at Chicago
Predrag Sukovic, Chief Executive Officer
Xoran Technologies
Gordana Vunjak-Novakovic, Professor
Department of Biomedical Engineering
Columbia University
The discussion will focus on the areas listed below as well as those that will emerge from the participants during the meeting:
- Identify near and mid-term opportunities for technology transfer to accelerated product development
- What incentives are needed to promote academia-industry partnerships?
- Can we identify and clear roadblocks that have gotten in the way of such partnerships in the past?
- How can we focus strategic initiatives on translation and commercialization of technologies in areas of greatest public need?
- What new models for multidisciplinary education are needed?
5:00–5:30 p.m. Summary, Recommendations and Next Steps
Rosemarie Hunziker, Program Director
Technology Development and Industrial Relations, NIDCR
- Highlights and accomplishments of the meeting and specific suggestions for follow up, future meetings, and programs
5:30 p.m. Adjourn