Welcome to the Dog Genome Project at the National Human Genome Research Institute (formerly at the Fred Hutchinson Cancer Research Center). We are working to develop resources necessary to map and clone canine genes in an effort to utilize dogs as a model system for genetics and cancer research.

Breed relationships facilitate fine-mapping studies: A 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds - a paper in Genome Research .

• Click here for the abstract or the full length paper.

• Supporting information for this paper can be found in Supplemental Info For Recent Publications page.

• See References for links to The Genetic Structure of the Purebred Domestic Dog

Owners of dogs who have taken part in cancer studies can submit updates of their dog's health.

Irish Wolfhound Health Update

Health Update for the Squamous Cell Carcinoma Study

Health Update for the Malignant Histiocytosis Study

Health Update for the Transitional Cell Carcinoma Study

Mastiff Health & Body Size Survey
For more information about current studies of Transitional Cell Carcinoma, Malignant Histiocytosis, Squamous Cell Carcinoma, Hemangiosarcoma, and T-Cell Lymphoma please contact us at: dog_genome@mail.nih.gov.

A Single IGF1 Allele Is a Major Determinant of Small Size in Dogs - a paper in Science Magazine.

• Click here for the abstract or the full length paper.

A Mutation in the Myostatin Gene Increases Muscle Mass and Enhances Racing Performance in Heterozygote Dogs - a paper in PLoS Genetics .

• Click here for the full length paper.

Supplemental Information for Recent Publications
Links to supporting methods, tables, and figures from recently published NHGRI Dog Genome Project and other Ostrander Group studies.

Methods and Protocols
Methods and protocols used in building the canine genomic map.

References
References to NHGRI Dog Genome Project publications in Canine research.

Links
Links to other canine and genome information resources.

Information for Dog Owners
An overview of the Dog Genome Research Project geared towards dog owners.

• Send questions and comments to dog_genome@mail.nih.gov