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TOXNET HELP TEXT - MUTI-DATABASES

Contents

SEARCH SCREEN

SEARCH RESULTS

SELECTED RECORD SCREEN

HOW THE SYSTEM SEARCHES FOR AND DISPLAYS RECORDS

ADVANCED SEARCHING FEATURES

RECOMMENDED BROWSERS

 

SEARCH SCREEN

Search for Benzene

Entering a Search Query

In the query box, enter one or more terms (e.g., benzene) which describe your search topic. These may be any combination of words, chemical names, and numbers, including Chemical Abstracts Services (CAS) Registry Numbers (RN). Common "stop words" such as "a," "an," "for," "the," and "it," although you may enter them, will not be searched.

Examples of search terms:

  • acetone
  • vinyl chloride
  • 67-64-1
  • 75-01-4
  • brain
  • dna adducts
  • skin tumors in mice
  • biomarkers
  • aflatoxin b1

The term(s) entered will be searched for in all MUTLI-DATABASE fields.

The search will be initiated when you click the Search button. To erase your search term(s) and start over with a blank query box, click on the Clear button.

Database Selection

You can choose to search one or several databases. The default selection is to search the multiple databases HSDB, CCRIS, IRIS, and GENE-TOX. If you choose not to search one or more of the databases, simply "uncheck" the corresponding check box(es).

Synonym Searching

If your query consists of chemicals, TOXNET will, by default (i.e., the radio button "Yes" is selected), expand your search by adding synonyms and CAS Registry Numbers. Thus, if you enter "perchloroethylene," the system will add the CAS RN 127-18-4 and synonyms such as "tetrachloroethylene" and "tetrachloroethene." You have the option to turn off this feature by selecting the button "No." This will result in a search only for the exact word(s) you entered. In the example above, the system would then look only for the word "perchloroethylene."

For typical queries, it is suggested that you leave the synonym searching feature on ("Yes" button selected) in order to maximize retrieval. On the other hand, if you were searching specifically for a brand name product, say "tylenol," and were interested only in records that mentioned the chemical with that name, you might want to turn off synonym searching ("No" button selected).

Browse the Index

Browse for Hexachlorobenzene

 

Results of Browse for Hexachlorobenzene

Clicking on the Browse the Index button will display a segment of the indexes for any combination of the HSDB, CCRIS, IRIS, and GENE-TOX databases, beginning with the term you enter (e.g., hexachlorobenzene), and let you scan the index alphabetically (or numerically) above or below the original display by clicking on the Up or Down button. For each index term, the system displays the number of records containing that term for each applicable database. By checking the "Check to Select" box(es) corresponding to the index term(s) of interest and clicking on the Select button, you can search on the selected term(s). Alternately, you can click on the number of records for any database and go directly to that database's search results. You may browse the index to all words, CAS Registry Numbers, or chemical names.

Databases (The Left Column of the Screen)

Clicking on any of the cells in this column will take you directly to the search screen for the database selected. The information icon ("i") next to each database provides a brief description of it, with links to a more detailed Fact Sheet and a sample record.

Other NLM Resources, Support Pages (The Right Column of the Screen)

You may also visit additional NLM Web-Based Resources:

  • DIRLINE - Directory of health and scientific organizations.
  • Tox Web Links - Links to additional toxicology Web sites.
  • MEDLINEplus Tox/Env Health - Consumer health information on toxicology and environmental health topics.
  • PubMed - Access to the MEDLINE database of biomedical literature.
  • NLM Gateway - Searches across multiple NLM databases.
  • Locatorplus - NLM's online catalog of books, audiovisuals, and journals.
Or Support Pages:
  • Help - Detailed documentation, such as what you are reading now, about searching TOXNET.

SEARCH RESULTS

About Your Search Results

Search Results for Benzene

Near the top of the screen are the summary results of numbers of records retrieved for each of the databases searched. Your initial retrieval is displayed as a list of chemical names, highlighted in blue and underlined, and their CAS Registry Numbers. If your search was for a chemical (e.g., benzene) and there is a match for it in one or more of the databases, the record for this chemical, referred to as the primary chemical record, will display first, one primary record for each database you have selected to search. This will be followed by a list of other chemical records in the databases selected, which also contain some mention of the chemical you entered. This latter list of chemicals is displayed according to a Relevancy Ranking algorithm. Clicking directly on any of the items will provide a display of the Selected Record Screen, containing all the data, for that item.

If your query consists of words that are not chemical terms, this same Relevancy Ranking algorithm determines the order of display of all your search results.

By checking one or more of the numbered boxes to the left of the list of records, you can perform operations, such as downloading, on these selections at a later time.

You can alter your search, if you choose, directly in the query box which reappears on this page with your search terms. Alternately, you can use the Modify Search button, described below.

The vertical series of buttons on the left side of the Search Results page offers a variety of options:

Save Checked Items � This is used to create a subset of your search results. First check the records you want to save, then click on Save Checked Items. The system confirms the number of items you saved and lets you display just these references by clicking on a new button - Display Saved Items - which is added to the series of buttons.

Sort � Sort all or some of the records alphabetically (in ascending or descending order) by substance name.

Details � Summarizes the strategy used by TOXNET to perform your search. This will include your query terms plus any synonyms or CAS Registry Numbers added by the system.

History � Reviews your search session by itemizing your search statements, numbering them sequentially, and listing the number of records retrieved. Clicking on History allows you to view earlier search result sets or combine these sets provided they are within the same database.

Download � You can download all or some of the records in "brief" or "full" formats and select particular categories of information (custom formats).

Modify Search � Return to the Basic Search screen with your search strategy retained. You can make changes or perform a new search at this point.

Basic Search - Return to the Basic Search screen with the query box cleared. You can now enter a new search.

Browse Index � Clicking on the Browse the Index button will display a segment of the indexes for any combination of the HSDB, CCRIS, IRIS, and GENE-TOX databases, beginning with the term you enter (e.g., hexachlorobenzene), and let you scan the index alphabetically (or numerically) above or below the original display by clicking on the Up or Down button. For each index term, the system displays the number of records containing that term for each applicable database. By checking the "Check to Select" box(es) corresponding to the index term(s) of interest and clicking on the Select button, you can search on the selected term(s). Alternately, you can click on the number of records for any database and go directly to that database's search results. You may browse the index to all words, CAS Registry Numbers, or chemical names.

TOXNET Home � Return to the TOXNET Home Page.

Page Navigation - The top and bottom of each Search Results page always displays the total number of items retrieved and the range of items displayed on the current page, and, depending on the number of search results, the current page number and the total number of pages. You can navigate through multi-page search results either by specifying a page number and clicking on the "Go" button or by using the blue arrows to go to the following or preceding page(s).


SELECTED RECORD SCREEN

About the Selected Record Screen

Benzene record

This screen displays the record for the item and database selected on the Search Results screen. If you search for a chemical (e.g., benzene) and then click on the "Primary Record" of the Search Results screen, you will see the entire record, along with a Table of Contents frame on the left. If you click on a different chemical record, the sections of the record best matching your query terms will be displayed (see Best Sections), again, with an accompanying Table of Contents. From the Table of Contents, you can then select to view portions of the record by expanding and contracting categories and selecting specific categories and/or fields of the record.

If your original search was for a term other than a chemical, any chemical record you click on from the Search Results screen will result in a "Best Sections" display.

The search term(s) you entered, as well as synonyms (if you selected to search for them), will all be highlighted in red wherever they appear in the text of the selected chemical record.

More detailed information is available for each of the databases - HSDB, CCRIS, IRIS, and GENE-TOX - by clicking on the "Help" link available on any of these databases' search screens.

Across the top of the screen is a series of buttons with more options:

Next Item - Move forward for a display of the next item (if there is one) in your search retrieval or saved items set.

Previous Item - Move backward for a display of the previous item (if there is one) in your search retrieval or saved items set.

Search Results - Return to the Search Results display.

Basic Search - Return to the Basic Search screen with the query box cleared so that you can enter a new search.

Details - Displays a summary of the strategy you specified for your search and synonyms added by the system.

Other Files - Link directly to records in the other TOXNET data files or in bibliographic files (e.g., TOXLINE) containing information on your selected chemical.

Modify Search - Return to the Basic Search screen with your search strategy retained. You can make changes or perform a new search at this point.

Download - You can download the selected record in "full" format and select particular categories of information (custom formats).

Browse Index - Clicking on the Browse the Index button will display a segment of the indexes for any combination of the HSDB, CCRIS, IRIS, and GENE-TOX databases, beginning with the term you enter (e.g., hexachlorobenzene), and let you scan the index alphabetically (or numerically) above or below the original display by clicking on the Up or Down button. For each index term, the system displays the number of records containing that term for each applicable database. By checking the "Check to Select" box(es) corresponding to the index term(s) of interest and clicking on the Select button, you can search on the selected term(s). Alternately, you can click on the number of records for any database and go directly to that database's search results. You may browse the index to all words, CAS Registry Numbers, or chemical names.

TOXNET Home - Return to the TOXNET Home Page.


HOW THE SYSTEM SEARCHES FOR AND DISPLAYS RECORDS

TOXNET searches for your terms, in singular and plural form, throughout all records unless you specify particular fields. The system will automatically look for synonyms and CAS Registry Numbers of chemicals unless you choose to disable this feature.


If you search on multiple terms, and each record retrieved contains all the terms you entered, the system will first display those records in which all the terms appear in the same section of the record. These records will be followed by records in which the terms appear in different sections of the record. If a multiple-term search fails to retrieve any records containing all the terms entered, the system will display the following message: "No records were found which contain all of the search words. The following records contain at least one of the words."


Relevancy ranking attempts to determine which documents are most pertinent to the search, and to place the most relevant documents first in the list of returned documents. The ranking is based upon the number of individual search terms occurring in a document, the number of times each search term occurs in a document, its rarity within the database, and the nearness of search terms to each other. Documents containing combinations of search words tend to be ranked higher than documents having isolated occurrences of the words.


In searching for a particular chemical, say "benzene," your retrieval may include chemical records in addition to the initial matching chemical record, called the "primary" record. These additional records appear if they contain the word "benzene." This might occur, for example, if the chemical is a metabolite of benzene, interacts with benzene, or has been tested along with benzene in a toxicity study.

Clicking on any of these non-primary chemicals on the Search Results screen will display the Best Sections, those where the chemical search term appears with greatest frequency. The term searched appears highlighted in red.

Another situation in which Best Sections would occur is in searching for a subject, say "DNA." In this case, clicking on any of the chemicals in the Search Results screen will display the Best Sections, i.e., the sections of the records where the word "DNA" appears with the greatest frequency.


ADVANCED SEARCHING FEATURES

Users seeking a finer degree of precision in retrieval than available through TOXNET's standard Basic Search screen may want to consider formulating searches through the use of Boolean logic.

Users seeking a finer degree of precision in retrieval than available through TOXNET's standard relevancy ranking methodology may want to consider formulating searches through the use of Boolean logic.

Boolean Searching utilizes the logical operators OR, AND, NOT. It is a means of limiting your search of two or more terms to criteria you specify. Logical operators must appear in upper case. Searches containing combinations of these operators are processed with ANDs taking precedence, followed by NOTs, and then followed by ORs. This default precedence may be overridden with the use of parentheses, which may also be nested (i.e., parentheses within parentheses).

  • OR - In searching Multi-Databases for records containing either the word "liver" or the word "kidney," you would enter "liver OR kidney." This would retrieve all records containing either of these words or both of them.
  • AND - This operator is used to search for the co-occurrence of two or more search terms. Thus, in Multi-Databases, to search for both the words "hepatocellular" and "carcinoma," you would enter "hepatocellular AND carcinoma."
  • NOT - This operator allows you to exclude terms from your search. To search in Multi-Databases for nervous system effects that do not involve the peripheral nervous system, you would enter "nervous NOT peripheral."
  • Parentheses - To search on effects seen in the uterus or thyroid of rats or mice, you would enter "(rats OR mice) AND (uterus OR thyroid)."

Truncation - The asterisk (*) may be freely used as a truncation symbol standing for any number of characters. Searching in Multi-Databases for spin* will retrieve records with words such as spine, spinal, spino, and spinally. Truncation may be used with or without Boolean searching.

Phrase Searching - In phrase searching, quotation marks ("�") are included as part of the search strategy and are used to search for two or more terms exactly the way they are entered. In Multi-Databases, a search for 'large intestine' would be phrased as follows: "large intestine". Phrase searching may be used with or without Boolean searching.


RECOMMENDED BROWSERS

TOXNET is best viewed with Internet Explorer 4.0 or Netscape 4.0 or higher versions, for either PC or Mac.