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Found 41 studies with search of:   Open Studies | "gene therapy"
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Rank Status Study
1 Recruiting Gene Therapy-Treated Stem Cells in Treating Patients Undergoing Stem Cell Transplant for Intermediate-Grade or High-Grade AIDS-Related Lymphoma
Condition: Lymphoma
Interventions: Drug: carmustine;   Drug: cyclophosphamide;   Drug: etoposide;   Drug: filgrastim;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: gene therapy;   Procedure: in vitro-treated peripheral blood stem cell transplantation
2 Recruiting Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)
Condition: Muscular Dystrophies
Interventions: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- Lower dose;   Genetic: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- Higher dose
3 Recruiting Gene Therapy With GX-12 in Combination With HAART for the HIV-1 Infected Patients
Condition: HIV Infections
Interventions: Genetic: GX-12;   Drug: HAART
4 Recruiting Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Conditions: Severe Combined Immunodeficiency;   Malignancy, Hematologic;   Neuroblastoma;   Neoplasm;   Mucopolysaccharidosis I
Intervention: Procedure: Venipuncture
5 Recruiting Phase III Randomized Trial of Suicide Gene Therapy and Prostate Cancer
Condition: Prostate Cancer
Interventions: Biological: Ad5-yCD/mutTKSR39rep-ADP;   Radiation: IMRT
6 Recruiting Safety Study of RPE65 Gene Therapy to Treat Leber Congenital Amaurosis
Condition: Retinal Degeneration
Intervention: Biological: tgAAG76 (rAAV 2/2.hRPE65p.hRPE65)
7 Recruiting Phase I - Pre-Radical Prostatectomy RTVP-1 Gene Therapy for Prostate Cancer
Condition: Prostatic Neoplasms
Intervention: Genetic: RTVP-1 Gene
8 Recruiting Retroviral Vector Mediated Globin Gene Transfer to Correct Sickle Cell Anemia or Thalaassemia
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention: Genetic: Gene Therapy
9 Recruiting Phase I Study Combining Suicide Gene Therapy With Chemoradiotherapy in the Treatment of Non-Metastatic Pancreatic Adenocarcinoma
Condition: Pancreatic Cancer
Intervention: Genetic: ad5-yCD/mutTKSR39rep-ADP
10 Recruiting Gene Therapy for Pleural Malignancies
Conditions: Pleural Mesothelioma;   Metastatic Pleural Effusions
Intervention: Gene Transfer: BG00001 (adenoviral-mediated interferon-beta)
11 Recruiting Gene Therapy for Chronic Granulomatous Disease
Condition: Chronic Granulomatous Disease
Intervention: Drug: Phagocyte Oxidase Subunit Transduced CD34 Hematopoietic Stem Cells
12 Recruiting Gene Therapy for Prostate Cancer That Returns After Radiation Therapy
Conditions: Prostatic Neoplasms;   Neoplasm Recurrence, Local
Intervention: Gene Transfer: Ad.hIL-12
13 Recruiting A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer
Condition: Prostate Cancer
Intervention: Biological: Gene Directed Enzyme Prodrug Therapy, FP253/Fludarabine
14 Recruiting Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)
Condition: Severe Combined Immunodeficiency
Intervention: Drug: Gene-Transduced Autologous CD34+ Stem Cells
15 Recruiting Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma
Conditions: Malignant Melanoma;   Neoplasm Metastasis
Intervention: Genetic: investigational drug INGN 241
16 Recruiting Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas
Conditions: Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma
Interventions: Biological: AdV-tk;   Drug: Valacyclovir
17 Recruiting Phase I/II Study of the Safety, Efficacy and Dose Evaluation of ProSavin for the Treatment of Bilateral Idiopathic Parkinson's Disease
Condition: Parkinson's Disease
Interventions: Biological: ProSavin;   Biological: ProSavin
18 Recruiting Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
Conditions: Healthy;   Sickle Cell Anemia
Intervention:
19 Not yet recruiting SERCA Gene Therapy Trial
Conditions: Advanced Heart Failure;   Patients That Have Received a Left Ventricular Assist Device
Interventions: Genetic: AAV6.SERCA2a;   Procedure: Placebo
20 Recruiting Gene Therapy, Valacyclovir, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Supratentorial Malignant Glioma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: adenoviral vector encoding HSV thymidine kinase;   Drug: valacyclovir;   Procedure: conventional surgery;   Procedure: neoadjuvant therapy;   Procedure: radiation therapy

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