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Office of Laboratory Animal Welfare
Notices

OLAW welcomes comments on any of its policy guidance. Comments may be submitted to OLAW by email at: olaw@od.nih.gov (please insert the title of the specific guidance document in the subject field), or by mail to:

Division of Policy and Education
Office for Laboratory Animal Welfare
National Institutes of Health
RKL 1, Suite 360, MSC 7982
6705 Rockledge Drive
Bethesda, MD 20892-7982

All relevant comments will be considered in OLAW decisions on timing and content of revisions to guidance documents, or development of new guidance documents. Comments generally will not result in direct responses from OLAW.

Disclaimer:
OLAW develops and monitors, as well as exercises compliance oversight relative to the Public Health Service Policy on Humane Care and Use of Laboratory Animals (the "PHS Policy"). One of OLAW's primary functions is to advise awarding units and awardee institutions concerning the implementation of the PHS Policy. OLAW often provides this advice by responding to policy-related questions submitted by such units and institutions. The following Notices provide guidance that represents OLAW's current thinking on these topics. This guidance is based on OLAW's experience with the subject matter and draws on best practices followed by the biomedical community regarding the use of research animals. Unless specific statutory or regulatory requirements are cited, the Notices should be viewed as recommendations in that an institution may use an alternative approach if the approach satisfies the requirements of the PHS Policy.

 

  • Download List of all current Notices in Word (MS Word - 225 KB)
  • January 8, 2009: Guidance to IACUCs Regarding Use of Designated Member Review (DMR) for Animal Study Proposal Review Subsequent to Full Committee Review (FCR)   New
  • February 15, 2008: Update of Sample Animal Welfare Assurance
  • October 12, 2007: Implementation of the Revised American Veterinary Medical Association Guidelines on Euthanasia
  • January 26, 2007: NIH Policy on Allowable Costs for Grant Activities Involving Animals when Terms and Conditions are not Upheld
  • March 24, 2006: Guidance on Use of Telecommunications for IACUC Meetings
  • February 24, 2005: Guidance on Prompt Reporting to OLAW under the PHS Policy on Humane Care and Use of Laboratory Animals
  • July 13, 2004: Standardization of Annual Report Due Dates, Consistent Reporting Periods, and Approval Periods for Assurance
  • June 6, 2003: Revised Guidance Regarding IACUC Approval of Changes in Personnel Involved in Animal Activities
  • July 17, 2002: Clarification Regarding Use of C02 for Euthanasia of Small Laboratory Animals
  • February 12, 2001: Guidance Regarding Administrative IACUC Issues (alternate IACUC members, IACUC review at collaborating institutions) and Efforts to Reduce Regulatory Burden
  • February 3, 2000: Guidance Concerning the Production of Monoclonal Antibodies in Animals
  • December 21, 1999: Guidance Regarding Reduction of Regulatory Burden
  • November 17, 1997: Production of Monoclonal Antibodies Using Mouse Ascites Method
  • June 2, 1997: Maintenance of Properly Constituted IACUCs
  • May 30, 1997: NASA Principles for the Ethical Care and Use of Animals
  • March 8 1995: Sources of Custom Antibody
  • Jan 14 1994: Requirements for Annual Reporting to OPRR
  • Jan 11 1994: Internal Distribution of Animal Welfare Assurances
  • May 21 1990: Use of Expedited Protocol Review Procedures by IACUCs
Archive of Outdated Notices

  • August 7, 2002 (PDF - 40 KB): Change in PHS Policy Concerning Submission of IACUC Approval
  • April 3, 2001: Implementation of the Revised AVMA Panel on Euthanasia Report
  • March 30, 2000 (PDF - 17 KB): Renaming of DAW/OPRR to Office of Laboratory Animal Welfare (OLAW)
  • July 31 1996: Implementation of the 1996 revision of the Guide for the Care and Use of Laboratory Animals
  • Jan 26 1996: Revision of the Guide for the Care and Use of Laboratory Animals
  • Oct 14 1994: National Survey of Laboratory Animal Use, Facilities, and Resources
  • 1990: Assistance To Institutions In Complying With Reporting Requirements of The PHS Policy

Questions and comments about the OLAW document library should be emailed to: OLAW: olaw@od.nih.gov



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