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Perinatal Guidelines
Public Health Service Task Force Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States - July 8, 2008
PDF Version (5.6 MB)
PDA Version (1.1 MB)
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Fact Sheets
HIV During Pregnancy, Labor and Delivery, and After Birth
Fact sheet series that provides information for women who are HIV positive and pregnant or have recently given birth. Describes the steps an HIV positive pregnant woman can take to preserve her health and prevent transmission of HIV to her baby.
PDF Version (179 KB)
Manuals
Drugs
Adapted from Perinatal Treatment Guidelines Table 3: Antiretroviral Drug Use in Pregnant HIV-Infected Women: Recomendations for Use in Pregnancy
NRTIs
PIs
Recommended Agents
Recommended Agents
Zidovudine
Lopinavir/ritonavir
Lamivudine
Alternate Agents
Alternate Agents
Indinavir
Didanosine
Nelfinavir
Emtricitabine
Ritonavir
Stavudine
Saquinavir
/
ritonavir
Abacavir
Insufficient Data to Recommend
Amprenavir
Insufficient Data to Recommend
Atazanavir
Tenofovir
Darunavir
Fosamprenavir
NNRTIs
Tipranavir
Recommended Agents
Nevirapine
Not Recommended
Efavirenz
Entry Inhibitors
Delavirdine
Insufficient Data to Recommend
Enfuvirtide
Integrase Inhibitor
Maraviroc
Insufficient Data to Recommend
Raltegravir
Health Topic
Citation
How to Cite the Perinatal Guidelines:
Perinatal HIV Guidelines Working Group. Public Health Service Task Force Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States. July 8, 2008; pp 1-98. Available at
http://aidsinfo.nih.gov/ContentFiles/PerinatalGL.pdf
. Accessed (insert Date) [include page numbers, table number, etc. if applicable]
Clinical Trials
24 studies were found.
Recruiting
Blood Levels of Tenofovir Gel in HIV Uninfected Pregnant Women Planning Cesarean Delivery
Condition: HIV Infections
En español
Recruiting
Antiviral Responses to a Nevirapine-Based Regimen Versus a Lopinavir/Ritonavir-Based Regimen in HIV Infected Infants Who Have or Have Not Received Single Dose Nevirapine for the Prevention of Mother-to-Child Transmission of HIV
Condition: HIV Infections
En español
Recruiting
Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth
Condition: HIV Infections
En español
Recruiting
Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women Who Take Nevirapine During Pregnancy
Condition: HIV Infections
En español
Recruiting
Tenofovir/Emtricitabine for PMTCT in Africa and Asia (ANRS 12109 TEmAA)
Condition: HIV Infection; Pregnancy
Not yet recruiting
Maternal and Infant Peripartum Nevirapine, Versus Infant Only Peripartum Nevirapine, or Maternal Lopinavir/Ritonavir in Addition to Standard Zidovudine Prophylaxis for the Prevention of Perinatal HIV in Thailand
Condition: HIV Infections; Pregnancy
Recruiting
Pharmacokinetics of Raltegravir During Third Trimester Pregnancy and Post-Partum
Condition: HIV Infections
Recruiting
The Effect of Pregnancy on the Pharmacokinetics of the Kaletra Tablet
Condition: Pregnancy; HIV
Recruiting
HSV-2 Suppression to Reduce Maternal HIV-1 RNA Levels During Pregnancy and Breastfeeding
Condition: HIV Infections; Herpes Simplex
Not yet recruiting
Daily Co-Trimoxazole Prophylaxis to Prevent Malaria in Pregnancy
Condition: Malaria in Pregnancy, With or Without HIV Infection
Recruiting
Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy
Condition: HIV Infections; Pregnancy
Recruiting
Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women
Condition: Pregnancy; HIV Infections; Sexually Transmitted Diseases
Not yet recruiting
Elizabeth Glaser Pediatric AIDS Foundation (EGPAF)Antiretroviral Pregnancy Registry A Multi-Site Protocol
Condition: HIV Infections; HIV Positive; Pregnant Women
Not yet recruiting
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy.
Condition: HIV; Malaria; HIV Infections
Not yet recruiting
Routine Use of Antiretroviral Therapy to Prevent Mother-to-Child HIV Transmission in the Kafue District of Zambia
Condition: HIV Infections
Recruiting
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
Condition: Infant, Newborn, Diseases; Sepsis; Puerperal Infection
Not yet recruiting
Community-Based Evaluation of a Pilot PMTCT Project in Kafue District
Condition: HIV-Free Survival; HIV Infections
Not yet recruiting
Pharmacokinetics of Generic Lopinavir/Ritonavir in Pregnant Women
Condition: HIV Infections
Not yet recruiting
Reducing HIV Risk Among Pregnant Women in Drug Treatment
Condition: HIV Risk Behavior
Recruiting
Multi-Level Interventions for STD Prevention Among Adolescents
Condition: Chlamydia
Recruiting
Multi-Sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant Women.
Condition: HIV Infections; Hepatitis B Virus
Recruiting
Development of Resistance Mutations in Pregnant HIV-Positive (+) Women Following Perinatal Antiretroviral Therapy in Israel
Condition: HIV Infections
Recruiting
Continuous Use of COCs
Condition: Pregnancy Prevention
Recruiting
Antiretroviral Drug Levels During and After Pregnancy
Condition: Pharmacokinetics
Important Notice:
This document has been submitted for publication to CDC's Morbidity and Mortality Weekly Report (MMWR) and should be considered a final draft. It is being posted on AIDS
info
to expedite dissemination of important clinical information. Upon acceptance and publication in MMWR, this draft will be removed and replaced by the published version. In the meantime, readers should be aware that the content of the draft might differ from the content of future published versions. Any corrections/questions concerning this document should be addressed to Ms. Jessica Carrington (e-mail: contactus@aidsinfo.nih.gov).