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Trial of amlodipine for patients with cervical dystonia receiving botulinum toxin injections

Botulinum Toxin Treatment Research Study

Trial of amlodipine for patients with cervical dystonia receiving botulinum toxin injections

We are looking for people with cervical dystonia or focal hand dystonia (writer's cramp) who are receiving botulinum toxin injections, but who improve less than 75% with injections or who have benefit lasting less than 2 months. We are trying to find out if amlodipine, a medication used for the treatment of high blood pressure, can improve the effect botulinum toxin injections for dystonia.

The study involveds approximately 10 outpatient visits lasting about 1 hour each to the NIH Clinical Center in Bethesda, MD over a 9 month period. 3 botulinum toxin injections will be provided during study participation as well as the study medication.

There is no cost for participation. Travel to and from NIH within the USA is provided for participants.

For more information, please contact:
Dr. Barbara Karp
Building 10; Room 6-5733
NINDS, NIH
Bethesda, MD 20892

Phone: 301-496-0150
Fax: 301-480-2973

Or Ms. Elizabeth Bartrum, CRNP
e-mail: bartrume@ninds.nih.gov


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