| | Other Issues: previous | next | latest | archiveCommentary Genetic interactions: the missing links for a better understanding of cancer susceptibility, progression and treatment Christopher A Maxwell, Víctor Moreno, Xavier Solé, Laia Gómez, Pilar Hernández, Ander Urruticoechea, and Miguel Angel Pujana Mol Cancer. 2008; 7: 4. Published online 2008 January 10. doi: 10.1186/1476-4598-7-4.PMCID: PMC2244643 Reviews The LIM and SH3 domain protein family: structural proteins or signal transducers or both? Thomas GP Grunewald and Elke Butt Mol Cancer. 2008; 7: 31. Published online 2008 April 17. doi: 10.1186/1476-4598-7-31.PMCID: PMC2359764 Evaluation of cell types for assessment of cytogenetic damage in arsenic exposed population Pritha Ghosh, Arindam Basu, Keshav K Singh, and Ashok K Giri Mol Cancer. 2008; 7: 45. Published online 2008 May 28. doi: 10.1186/1476-4598-7-45.PMCID: PMC2430711 Apoptotic pathways in pancreatic ductal adenocarcinoma Rainer Hamacher, Roland M Schmid, Dieter Saur, and Günter Schneider Mol Cancer. 2008; 7: 64. Published online 2008 July 24. doi: 10.1186/1476-4598-7-64.PMCID: PMC2515336 DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update Paul P Anglim, Todd A Alonzo, and Ite A Laird-Offringa Mol Cancer. 2008; 7: 81. Published online 2008 October 23. doi: 10.1186/1476-4598-7-81.PMCID: PMC2585582 The prince and the pauper. A tale of anticancer targeted agents Alfonso Dueñas-González, Patricia García-López, Luis Alonso Herrera, Jose Luis Medina-Franco, Aurora González-Fierro, and Myrna Candelaria Mol Cancer. 2008; 7: 82. Published online 2008 October 23. doi: 10.1186/1476-4598-7-82.PMCID: PMC2615789 Tissue Inhibitor of Metalloproteinases-4. The road less traveled Jorge Melendez-Zajgla, Luis Del Pozo, Gisela Ceballos, and Vilma Maldonado Mol Cancer. 2008; 7: 85. Published online 2008 November 21. doi: 10.1186/1476-4598-7-85.PMCID: PMC2599898 Short Communications Intravenous administration of the conditionally replicative adenovirus Ad5-Δ24RGD induces regression of osteosarcoma lung metastases Harm CA Graat, Victor W van Beusechem, Frederik HE Schagen, M Adhiambo Witlox, Eugenie S Kleinerman, Marco N Helder, Winald R Gerritsen, Gertjan JL Kaspers, and Paul IJM Wuisman Mol Cancer. 2008; 7: 9. Published online 2008 January 23. doi: 10.1186/1476-4598-7-9.PMCID: PMC2254437 A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice Alice C Fan, Marianna M Goldrick, Jennifer Ho, Yu Liang, Pavan Bachireddy, and Dean W Felsher Mol Cancer. 2008; 7: 74. Published online 2008 September 30. doi: 10.1186/1476-4598-7-74.PMCID: PMC2572631 Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties? Puri Catalina, Rosa Montes, Gertru Ligero, Laura Sanchez, Teresa de la Cueva, Clara Bueno, Paola E Leone, and Pablo Menendez Mol Cancer. 2008; 7: 76. Published online 2008 October 3. doi: 10.1186/1476-4598-7-76.PMCID: PMC2567976 Bone marrow ectopic expression of a non-coding RNA in childhood T-cell acute lymphoblastic leukemia with a novel t(2;11)(q11.2;p15.1) translocation Maria Corsignano Guastadisegni, Angelo Lonoce, Luciana Impera, Francesco Albano, Pietro D'Addabbo, Sebastiano Caruso, Isabella Vasta, Ioannis Panagopoulos, Anna Leszl, Giuseppe Basso, Mariano Rocchi, and Clelia Tiziana Storlazzi Mol Cancer. 2008; 7: 80. Published online 2008 October 23. doi: 10.1186/1476-4598-7-80.PMCID: PMC2579299 Editorials To know or not to know: archiving and the under-appreciated historical value of data David Covarrubias, Maurice Van Emburgh, Hassan R Naqvi, Christian Schmidt, and Shawn Mathur Mol Cancer. 2008; 7: 18. Published online 2008 February 11. doi: 10.1186/1476-4598-7-18.PMCID: PMC2257976 Another challenge for scientists Laura M Christian, Hassan R Naqvi, Christian Schmidt, David Covarrubias, and Shawn Mathur Mol Cancer. 2008; 7: 63. Published online 2008 July 17. doi: 10.1186/1476-4598-7-63.PMCID: PMC2517074 The problem of choice Hassan R Naqvi, Shawn Mathur, David Covarrubias, Josephine A Curcio, and Christian Schmidt Mol Cancer. 2008; 7: 86. Published online 2008 November 23. doi: 10.1186/1476-4598-7-86.PMCID: PMC2599897 Research Identification and transcript analysis of a novel wallaby (Macropus eugenii) basal-like breast cancer cell line Julie A Sharp, Sonia L Mailer, Peter C Thomson, Christophe Lefèvre, and Kevin R Nicholas Mol Cancer. 2008; 7: 1. Published online 2008 January 7. doi: 10.1186/1476-4598-7-1.PMCID: PMC2263075 Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines Faisal M Fadlelmola, Minglong Zhou, Ronald J de Leeuw, Nirpjit S Dosanjh, Karynn Harmer, David Huntsman, Wan L Lam, and Diponkar Banerjee Mol Cancer. 2008; 7: 2. Published online 2008 January 7. doi: 10.1186/1476-4598-7-2.PMCID: PMC2254646 Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer Jose Diaz-Chavez, Rogelio Hernandez-Pando, Paul F Lambert, and Patricio Gariglio Mol Cancer. 2008; 7: 3. Published online 2008 January 9. doi: 10.1186/1476-4598-7-3.PMCID: PMC2248208 The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer Fan Cheng, Patricia J McLaughlin, Michael F Verderame, and Ian S Zagon Mol Cancer. 2008; 7: 5. Published online 2008 January 11. doi: 10.1186/1476-4598-7-5.PMCID: PMC2253554 Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile Ingrid Cifola, Roberta Spinelli, Luca Beltrame, Clelia Peano, Ester Fasoli, Stefano Ferrero, Silvano Bosari, Stefano Signorini, Francesco Rocco, Roberto Perego, Vanessa Proserpio, Francesca Raimondo, Paolo Mocarelli, and Cristina Battaglia Mol Cancer. 2008; 7: 6. Published online 2008 January 14. doi: 10.1186/1476-4598-7-6.PMCID: PMC2253555 Differential expression of metallothioneins (MTs) 1, 2, and 3 in response to zinc treatment in human prostate normal and malignant cells and tissues Hua Wei, Mohamed Mokhtar Desouki, Shufei Lin, Dakai Xiao, Renty B Franklin, and Pei Feng Mol Cancer. 2008; 7: 7. Published online 2008 January 21. doi: 10.1186/1476-4598-7-7.PMCID: PMC2265743 An integrative model for recurrence in ovarian cancer Alexandros Laios, Sharon A O'Toole, Richard Flavin, Cara Martin, Martina Ring, Noreen Gleeson, Tom D'Arcy, Eamonn PJ McGuinness, Orla Sheils, Brian L Sheppard, and John J O' Leary Mol Cancer. 2008; 7: 8. Published online 2008 January 22. doi: 10.1186/1476-4598-7-8.PMCID: PMC2248209 Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors Samy L Habib, Simona Simone, Jeff J Barnes, and Hanna E Abboud Mol Cancer. 2008; 7: 10. Published online 2008 January 24. doi: 10.1186/1476-4598-7-10.PMCID: PMC2265742 Gene expression profiles in primary pancreatic tumors and metastatic lesions of Ela-c-myc transgenic mice Archana Thakur, Aliccia Bollig, Jiusheng Wu, and Dezhong J Liao Mol Cancer. 2008; 7: 11. Published online 2008 January 24. doi: 10.1186/1476-4598-7-11.PMCID: PMC2259361 Constitutive overexpression of a novel 21 kDa protein by Hodgkin Lymphoma and Aggressive Non-Hodgkin Lymphomas Minglong Zhou, Faisal M Fadlelmola, Jason B Cohn, Brian Skinnider, Randy D Gascoyne, and Diponkar Banerjee Mol Cancer. 2008; 7: 12. Published online 2008 January 24. doi: 10.1186/1476-4598-7-12.PMCID: PMC2267462 Insulin-like growth factor-I gene therapy reverses morphologic changes and reduces hyperprolactinemia in experimental rat prolactinomas Gloria M Console, Claudia B Herenu, Gisela A Camihort, Georgina C Luna, Maria I Bracamonte, Gustavo R Morel, and Rodolfo G Goya Mol Cancer. 2008; 7: 13. Published online 2008 January 25. doi: 10.1186/1476-4598-7-13.PMCID: PMC2263076 Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells Nadia Vié, Virginie Copois, Caroline Bascoul-Mollevi, Vincent Denis, Nicole Bec, Bruno Robert, Caroline Fraslon, Emmanuel Conseiller, Franck Molina, Christian Larroque, Pierre Martineau, Maguy Del Rio, and Céline Gongora Mol Cancer. 2008; 7: 14. Published online 2008 January 25. doi: 10.1186/1476-4598-7-14.PMCID: PMC2245978 DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines J Devon Roll, Ashley G Rivenbark, Wendell D Jones, and William B Coleman Mol Cancer. 2008; 7: 15. Published online 2008 January 25. doi: 10.1186/1476-4598-7-15.PMCID: PMC2246151 Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis Sharmila Shankar, Suthakar Ganapathy, Qinghe Chen, and Rakesh K Srivastava Mol Cancer. 2008; 7: 16. Published online 2008 January 29. doi: 10.1186/1476-4598-7-16.PMCID: PMC2249593 Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide Shi Yu Yang, Kevin M Sales, Barry J Fuller, Alexander M Seifalian, and Marc C Winslet Mol Cancer. 2008; 7: 17. Published online 2008 February 8. doi: 10.1186/1476-4598-7-17.PMCID: PMC2276513 Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivo Xinrui Yan, Mei-Sze Chua, Jing He, and Samuel K So Mol Cancer. 2008; 7: 19. Published online 2008 February 12. doi: 10.1186/1476-4598-7-19.PMCID: PMC2276234 Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model Alan A Arnold, Amro Aboukameel, Jianyong Chen, Dajun Yang, Shaomeng Wang, Ayad Al-Katib, and Ramzi M Mohammad Mol Cancer. 2008; 7: 20. Published online 2008 February 14. doi: 10.1186/1476-4598-7-20.PMCID: PMC2265299 Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma Madeleine Austinat, Ruediger Dunsch, Christian Wittekind, Andrea Tannapfel, Rolf Gebhardt, and Frank Gaunitz Mol Cancer. 2008; 7: 21. Published online 2008 February 18. doi: 10.1186/1476-4598-7-21.PMCID: PMC2287186 In Silico analysis of Gastric carcinoma Serial Analysis of Gene Expression libraries reveals different profiles associated with ethnicity Francisco J Ossandon, Cynthia Villarroel, Francisco Aguayo, Eudocia Santibanez, Naohide Oue, Wataru Yasui, and Alejandro H Corvalan Mol Cancer. 2008; 7: 22. Published online 2008 February 27. doi: 10.1186/1476-4598-7-22.PMCID: PMC2323622 Lymphangiogenesis and lymph node metastasis in breast cancer Giles H Cunnick, Wen G Jiang, Tony Douglas-Jones, Gareth Watkins, Kelvin F Gomez, Mike J Morgan, Ashok Subramanian, Kefah Mokbel, and Robert E Mansel Mol Cancer. 2008; 7: 23. Published online 2008 March 6. doi: 10.1186/1476-4598-7-23.PMCID: PMC2278160 Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin Kyunghee Burkitt and Mats Ljungman Mol Cancer. 2008; 7: 24. Published online 2008 March 6. doi: 10.1186/1476-4598-7-24.PMCID: PMC2276233 The Involvement of Bax in Zinc-Induced Mitochondrial Apoptogenesis in Malignant Prostate Cells Pei Feng, Tieluo Li, Zhixin Guan, Renty B Franklin, and Leslie C Costello Mol Cancer. 2008; 7: 25. Published online 2008 March 10. doi: 10.1186/1476-4598-7-25.PMCID: PMC2329666 Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells Anna Jankowska, Samuel I Gunderson, Miroslaw Andrusiewicz, Beata Burczynska, Anna Szczerba, Artur Jarmolowski, Ewa Nowak-Markwitz, and Jerzy B Warchol Mol Cancer. 2008; 7: 26. Published online 2008 March 14. doi: 10.1186/1476-4598-7-26.PMCID: PMC2335103 Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity Audrey Sermeus, Jean-Philippe Cosse, Marianne Crespin, Veronique Mainfroid, Francoise de Longueville, Noelle Ninane, Martine Raes, Jose Remacle, and Carine Michiels Mol Cancer. 2008; 7: 27. Published online 2008 March 26. doi: 10.1186/1476-4598-7-27.PMCID: PMC2330149 Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines Kimberly A Elliott, Lee F Rickords, and J Marcelete Labrum Mol Cancer. 2008; 7: 28. Published online 2008 March 26. doi: 10.1186/1476-4598-7-28.PMCID: PMC2346477 Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1 Mollie H Wright, Ana I Robles, Jason I Herschkowitz, Melinda G Hollingshead, Miriam R Anver, Charles M Perou, and Lyuba Varticovski Mol Cancer. 2008; 7: 29. Published online 2008 April 7. doi: 10.1186/1476-4598-7-29.PMCID: PMC2329667 Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome Hélène Lelièvre, Véronique Chevrier, Anne-Marie Tassin, and Daniel Birnbaum Mol Cancer. 2008; 7: 30. Published online 2008 April 15. doi: 10.1186/1476-4598-7-30.PMCID: PMC2373309 DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein Jing An, Dong-Yan Yang, Qin-Zhi Xu, Shi-Meng Zhang, Yan-Ying Huo, Zeng-Fu Shang, Yu Wang, De-Chang Wu, and Ping-Kun Zhou Mol Cancer. 2008; 7: 32. Published online 2008 April 22. doi: 10.1186/1476-4598-7-32.PMCID: PMC2383926 Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy Therese Seierstad, Kathrine Røe, Beathe Sitter, Jostein Halgunset, Kjersti Flatmark, Anne H Ree, Dag Rune Olsen, Ingrid S Gribbestad, and Tone F Bathen Mol Cancer. 2008; 7: 33. Published online 2008 April 25. doi: 10.1186/1476-4598-7-33.PMCID: PMC2377266 Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation Giorgia Egidy, Sophia Julé, Philippe Bossé, Florence Bernex, Claudine Geffrotin, Silvia Vincent-Naulleau, Vratislav Horak, Xavier Sastre-Garau, and Jean-Jacques Panthier Mol Cancer. 2008; 7: 34. Published online 2008 April 28. doi: 10.1186/1476-4598-7-34.PMCID: PMC2387171 Potential role of miR-9 and miR-223 in recurrent ovarian cancer Alexandros Laios, Sharon O'Toole, Richard Flavin, Cara Martin, Lynn Kelly, Martina Ring, Stephen P Finn, Ciara Barrett, Massimo Loda, Noreen Gleeson, Tom D'Arcy, Eamonn McGuinness, Orla Sheils, Brian Sheppard, and John O' Leary Mol Cancer. 2008; 7: 35. Published online 2008 April 28. doi: 10.1186/1476-4598-7-35.PMCID: PMC2383925 DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk Dominique Bernard-Gallon, Rémy Bosviel, Laetitia Delort, Luc Fontana, Alain Chamoux, Nadège Rabiau, Fabrice Kwiatkowski, Nasséra Chalabi, Samir Satih, and Yves-Jean Bignon Mol Cancer. 2008; 7: 36. Published online 2008 May 2. doi: 10.1186/1476-4598-7-36.PMCID: PMC2394522 Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain Purna Mukherjee, Tiernan J Mulrooney, Jeremy Marsh, Derek Blair, Thomas C Chiles, and Thomas N Seyfried Mol Cancer. 2008; 7: 37. Published online 2008 May 12. doi: 10.1186/1476-4598-7-37.PMCID: PMC2397440 COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro Huan-Ching Chuang, Adel Kardosh, Kevin J Gaffney, Nicos A Petasis, and Axel H Schönthal Mol Cancer. 2008; 7: 38. Published online 2008 May 16. doi: 10.1186/1476-4598-7-38.PMCID: PMC2396175 Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas Kenneth A Field, Soratree Charoenthongtrakul, J Michael Bishop, and Yosef Refaeli Mol Cancer. 2008; 7: 39. Published online 2008 May 19. doi: 10.1186/1476-4598-7-39.PMCID: PMC2409375 Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma David T Yang, Ken H Young, Brad S Kahl, Stephanie Markovina, and Shigeki Miyamoto Mol Cancer. 2008; 7: 40. Published online 2008 May 19. doi: 10.1186/1476-4598-7-40.PMCID: PMC2408930 Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile François Ducray, Ahmed Idbaih, Aurélien de Reyniès, Ivan Bièche, Joëlle Thillet, Karima Mokhtari, Séverine Lair, Yannick Marie, Sophie Paris, Michel Vidaud, Khê Hoang-Xuan, Olivier Delattre, Jean-Yves Delattre, and Marc Sanson Mol Cancer. 2008; 7: 41. Published online 2008 May 20. doi: 10.1186/1476-4598-7-41.PMCID: PMC2415112 Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line Yukio Nishimura, Kiyoko Yoshioka, Biborka Bereczky, and Kazuyuki Itoh Mol Cancer. 2008; 7: 42. Published online 2008 May 21. doi: 10.1186/1476-4598-7-42.PMCID: PMC2412912 Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors Laura Menendez, L DeEtte Walker, Lilya V Matyunina, Kimberly A Totten, Benedict B Benigno, and John F McDonald Mol Cancer. 2008; 7: 43. Published online 2008 May 22. doi: 10.1186/1476-4598-7-43.PMCID: PMC2429914 ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells Karen Denning, Paul Smyth, Susanne Cahill, Jinghuan Li, Richard Flavin, Sinead Aherne, John J O' Leary, and Orla Sheils Mol Cancer. 2008; 7: 44. Published online 2008 May 27. doi: 10.1186/1476-4598-7-44.PMCID: PMC2423371 Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms Shikha Gaur, John E Shively, Yun Yen, and Rajesh K Gaur Mol Cancer. 2008; 7: 46. Published online 2008 May 28. doi: 10.1186/1476-4598-7-46.PMCID: PMC2490704 Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of Head and Neck cancers Samah Abu-Ali, Abbas Fotovati, and Kanemitsu Shirasuna Mol Cancer. 2008; 7: 47. Published online 2008 June 3. doi: 10.1186/1476-4598-7-47.PMCID: PMC2464604 DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH Stine H Kresse, Magne Skårn, Hege O Ohnstad, Heidi M Namløs, Bodil Bjerkehagen, Ola Myklebost, and Leonardo A Meza-Zepeda Mol Cancer. 2008; 7: 48. Published online 2008 June 3. doi: 10.1186/1476-4598-7-48.PMCID: PMC2442610 Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway Brian J Wilson and Vincent Giguère Mol Cancer. 2008; 7: 49. Published online 2008 June 4. doi: 10.1186/1476-4598-7-49.PMCID: PMC2430971 Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity Valérie Combaret, Sandrine Boyault, Isabelle Iacono, Stéphanie Brejon, Raphaël Rousseau, and Alain Puisieux Mol Cancer. 2008; 7: 50. Published online 2008 June 5. doi: 10.1186/1476-4598-7-50.PMCID: PMC2442611 Transformation of MCF-10A cells by random mutagenesis with frameshift mutagen ICR191: A model for identifying candidate breast-tumor suppressors Helena Zientek-Targosz, Dimiter Kunnev, Lesleyann Hawthorn, Mikhail Venkov, Sei-Ichi Matsui, Richard T Cheney, and Yuri Ionov Mol Cancer. 2008; 7: 51. Published online 2008 June 5. doi: 10.1186/1476-4598-7-51.PMCID: PMC2430587 Involvement of GTA protein NC2β in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Veronica Giunta, Antonella Rapisarda, Elisa Tricarichi, Marco Miceli, Rosario Angelica, Agata Grillo, Barbara Banelli, Isabella Defferari, Stefano Forte, Alessandro Laganà, Camillo Bosco, Rosalba Giugno, Alfredo Pulvirenti, Alfredo Ferro, Karl H Grzeschik, Andrea Di Cataldo, Gian P Tonini, Massimo Romani, and Michele Purrello Mol Cancer. 2008; 7: 52. Published online 2008 June 6. doi: 10.1186/1476-4598-7-52.PMCID: PMC2443168 Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients Peyman Björklund, Daniel Lindberg, Göran Åkerström, and Gunnar Westin Mol Cancer. 2008; 7: 53. Published online 2008 June 9. doi: 10.1186/1476-4598-7-53.PMCID: PMC2435117 Resistance of mitochondrial p53 to dominant inhibition Kristina Heyne, Katrin Schmitt, Daniel Mueller, Vivienne Armbruester, Pedro Mestres, and Klaus Roemer Mol Cancer. 2008; 7: 54. Published online 2008 June 12. doi: 10.1186/1476-4598-7-54.PMCID: PMC2440547 Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells Annick Mühlethaler-Mottet, Roland Meier, Marjorie Flahaut, Katia Balmas Bourloud, Katya Nardou, Jean-Marc Joseph, and Nicole Gross Mol Cancer. 2008; 7: 55. Published online 2008 June 12. doi: 10.1186/1476-4598-7-55.PMCID: PMC2442609 Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy Ramaswamy Bhuvaneswari, Yik Y Gan, Sasidharan S Lucky, William WL Chin, Seyed M Ali, Khee C Soo, and Malini Olivo Mol Cancer. 2008; 7: 56. Published online 2008 June 13. doi: 10.1186/1476-4598-7-56.PMCID: PMC2440549 Identification of metabolites with anticancer properties by computational metabolomics Adrian K Arakaki, Roman Mezencev, Nathan J Bowen, Ying Huang, John F McDonald, and Jeffrey Skolnick Mol Cancer. 2008; 7: 57. Published online 2008 June 17. doi: 10.1186/1476-4598-7-57.PMCID: PMC2453147 Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha Luigi Scotto, Gopeshwar Narayan, Subhadra V Nandula, Shivakumar Subramaniyam, Andreas M Kaufmann, Jason D Wright, Bhavana Pothuri, Mahesh Mansukhani, Achim Schneider, Hugo Arias-Pulido, and Vundavalli V Murty Mol Cancer. 2008; 7: 58. Published online 2008 June 17. doi: 10.1186/1476-4598-7-58.PMCID: PMC2440550 Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells Tamer E Fandy, Sharmila Shankar, and Rakesh K Srivastava Mol Cancer. 2008; 7: 60. Published online 2008 June 30. doi: 10.1186/1476-4598-7-60.PMCID: PMC2474652 Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis Ying Liu, Joshua A Parry, Anna Chin, Stefan Duensing, and Anette Duensing Mol Cancer. 2008; 7: 61. Published online 2008 July 10. doi: 10.1186/1476-4598-7-61.PMCID: PMC2481267 Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer Paul P Anglim, Janice S Galler, Michael N Koss, Jeffrey A Hagen, Sally Turla, Mihaela Campan, Daniel J Weisenberger, Peter W Laird, Kimberly D Siegmund, and Ite A Laird-Offringa Mol Cancer. 2008; 7: 62. Published online 2008 July 10. doi: 10.1186/1476-4598-7-62.PMCID: PMC2483990 The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3 Sunita K Agarwal, William F Simonds, and Stephen J Marx Mol Cancer. 2008; 7: 65. Published online 2008 August 7. doi: 10.1186/1476-4598-7-65.PMCID: PMC2519076 Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines Elena Morandi, Cinzia Severini, Daniele Quercioli, Giovanni D'Ario, Stefania Perdichizzi, Miriam Capri, Giovanna Farruggia, Maria Grazia Mascolo, Wolfango Horn, Monica Vaccari, Roberto Serra, Annamaria Colacci, and Paola Silingardi Mol Cancer. 2008; 7: 66. Published online 2008 August 11. doi: 10.1186/1476-4598-7-66.PMCID: PMC2556695 Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression Frida Hansson, Jacek Toporski, Robert Månsson, Bertil Johansson, Ulrika Norén-Nyström, Sten Eirik W Jacobsen, Thomas Wiebe, Marcus Larsson, Mikael Sigvardsson, and Anders Castor Mol Cancer. 2008; 7: 67. Published online 2008 August 11. doi: 10.1186/1476-4598-7-67.PMCID: PMC2525657 Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study Hassan Brim, Pooneh Mokarram, Fakhraddin Naghibalhossaini, Mehdi Saberi-Firoozi, Mansour Al-Mandhari, Kamla Al-Mawaly, Rayhaneh Al-Mjeni, Abeer Al-Sayegh, Sandy Raeburn, Edward Lee, Francis Giardiello, Duane T Smoot, Alexander Vilkin, C Richard Boland, Ajay Goel, Mitra Hafezi, Mehdi Nouraie, and Hassan Ashktorab Mol Cancer. 2008; 7: 68. Published online 2008 August 21. doi: 10.1186/1476-4598-7-68.PMCID: PMC2551625 Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK Klaus Dittmann, Claus Mayer, Rainer Kehlbach, and H Peter Rodemann Mol Cancer. 2008; 7: 69. Published online 2008 September 12. doi: 10.1186/1476-4598-7-69.PMCID: PMC2546440 Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells Marielle Dejligbjerg, Morten Grauslund, Thomas Litman, Laura Collins, Xiaozhong Qian, Michael Jeffers, Henri Lichenstein, Peter Buhl Jensen, and Maxwell Sehested Mol Cancer. 2008; 7: 70. Published online 2008 September 12. doi: 10.1186/1476-4598-7-70.PMCID: PMC2553797 Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome Wen G Jiang, Tracey A Martin, Jonathan M Lewis-Russell, Anthony Douglas-Jones, Lin Ye, and Robert E Mansel Mol Cancer. 2008; 7: 71. Published online 2008 September 16. doi: 10.1186/1476-4598-7-71.PMCID: PMC2553413 Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover Carsten Denkert, Jan Budczies, Wilko Weichert, Gert Wohlgemuth, Martin Scholz, Tobias Kind, Silvia Niesporek, Aurelia Noske, Anna Buckendahl, Manfred Dietel, and Oliver Fiehn Mol Cancer. 2008; 7: 72. Published online 2008 September 18. doi: 10.1186/1476-4598-7-72.PMCID: PMC2569965 Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells Pinella Buongiorno, Vaijayanti V Pethe, George S Charames, Susmita Esufali, and Bharati Bapat Mol Cancer. 2008; 7: 73. Published online 2008 September 30. doi: 10.1186/1476-4598-7-73.PMCID: PMC2565678 Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma Eric Smith, Neville J De Young, Sandra J Pavey, Nicholas K Hayward, Derek J Nancarrow, David C Whiteman, B Mark Smithers, Andrew R Ruszkiewicz, Andrew D Clouston, David C Gotley, Peter G Devitt, Glyn G Jamieson, and Paul A Drew Mol Cancer. 2008; 7: 75. Published online 2008 October 2. doi: 10.1186/1476-4598-7-75.PMCID: PMC2567345 A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding Emily Ray Ko, Dennis Ko, Carolyn Chen, and Joseph S Lipsick Mol Cancer. 2008; 7: 77. Published online 2008 October 7. doi: 10.1186/1476-4598-7-77.PMCID: PMC2572630 Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival Chun-Liang Chen, Ling Cen, Jennifer Kohout, Brian Hutzen, Christina Chan, Fu-Chuan Hsieh, Abbey Loy, Victor Huang, Gong Cheng, and Jiayuh Lin Mol Cancer. 2008; 7: 78. Published online 2008 October 21. doi: 10.1186/1476-4598-7-78.PMCID: PMC2577686 Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes Teresa WM Fan, Magda Kucia, Kacper Jankowski, Richard M Higashi, Janina Ratajczak, Marius Z Ratajczak, and Andrew N Lane Mol Cancer. 2008; 7: 79. Published online 2008 October 21. doi: 10.1186/1476-4598-7-79.PMCID: PMC2577687 Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer Jürgen Veeck, Erik Noetzel, Nuran Bektas, Edgar Jost, Arndt Hartmann, Ruth Knüchel, and Edgar Dahl Mol Cancer. 2008; 7: 83. Published online 2008 November 6. doi: 10.1186/1476-4598-7-83.PMCID: PMC2613402 ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells Jan S Moreb, Henry V Baker, Lung-Ji Chang, Maria Amaya, M Cecilia Lopez, Blanca Ostmark, and Wayne Chou Mol Cancer. 2008; 7: 87. Published online 2008 November 24. doi: 10.1186/1476-4598-7-87.PMCID: PMC2605459 Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling Sinéad T Aherne, Paul C Smyth, Richard J Flavin, Susan M Russell, Karen M Denning, Jing Huan Li, Simone M Guenther, John J O'Leary, and Orla M Sheils Mol Cancer. 2008; 7: 89. Published online 2008 December 4. doi: 10.1186/1476-4598-7-89.PMCID: PMC2612696 Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells Yekaterina Y Zaytseva, Xin Wang, R Chase Southard, Natalie K Wallis, and Michael W Kilgore Mol Cancer. 2008; 7: 90. Published online 2008 December 5. doi: 10.1186/1476-4598-7-90.PMCID: PMC2614423 Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context Massimiliano Monticone, Emanuela Biollo, Massimo Maffei, Alessandra Donadini, Francesco Romeo, Clelia Tiziana Storlazzi, Walter Giaretti, and Patrizio Castagnola Mol Cancer. 2008; 7: 92. Published online 2008 December 16. doi: 10.1186/1476-4598-7-92.PMCID: PMC2615043 Correction Involvement of GTA protein NC2beta in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Veronica Giunta, Antonella Rapisarda, Elisa Tricarichi, Marco Miceli, Rosario Angelica, Agata Grillo, Barbara Banelli, Isabella Defferari, Stefano Forte, Alessandro Laganà, Camillo Bosco, Rosalba Giugno, Alfredo Pulvirenti, Alfredo Ferro, Karl H Grzeschik, Andrea Di Cataldo, Gian P Tonini, Massimo Romani, and Michele Purrello Mol Cancer. 2008; 7: 59. Published online 2008 June 30. doi: 10.1186/1476-4598-7-59.PMCID: PMC2474651 Corrects: Cinzia Di Pietro, et al. Involvement of GTA protein NC2β in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation. Mol Cancer. 2008; 7: 52. |