Protocol Number: 07-CC-0153
Patients 18 years of age and older who are scheduled to receive a stem cell transplant may be eligible for this study. Participants undergo the following procedures: Review of medical records Interview about their oral care Oral examination Collection of oral specimens just before the stem cell transplant, immediately after the transplant, and 3 weeks after the transplant. The specimens are obtained as follows: ? -About one-fourth teaspoon of saliva is collected with a suction device similar to that used in a dental office. ? -Plaque from the surface of a tooth is collected with a plastic toothpick. ? -Skin cells from the inside of the cheek and the surface of the tongue are collected with a small soft brush. ? -If a tube is inserted into the patient's lungs to assist breathing and the patient is admitted to the intensive care unit, a specimen from the lungs is collected. Patients are followed for 100 days after their transplant. Additional oral specimens are obtained from those who develop signs and symptoms of respiratory infection.
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National Institutes of Health Clinical Center
Bethesda, Maryland 20892. Last update: 01/17/2009
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