Influenza Virus Resource presents data obtained from the NIAID Influenza Genome Sequencing Project as well as from GenBank, combined with tools for flu sequence analysis and annotation. In addition, it provides links to other resources that contain flu sequences, publications and general information about flu viruses.

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Flu database |

NIAID Influenza Sequencing Project |

Influenza virus biology

NCBI Growth of flu sequences GenBank sequences from the NIAID Project Assembly Archive Trace Archive NIAID data releasing status RefSeq genomes RefSeq proteins Protein Structures Flu resources NIAID Project JCVI Flu CDC Flu Vaccine Selection WHO Flu NCBI Viruses Viral Genomes Virus Variation Dengue virus Retroviruses SARS-CoV Collaborators Canterbury Health Laboratories Ohio State University St. Jude Children's Research Hospital Surveillance Data, Inc. Wadsworth-NYSDOH

11/04/2008: Proteins belong to segments that encode more than one protein (e.g. M1 and M2) can now be searched separately from the database. More news Search the Flu database, build queries, retrieve sequences, apply analysis tools Begin Database Select influenza sequences by virus, subtype, host, and other criteria Advanced database search Genome Set Find complete genome sets Alignment Align your sequence(s) and others in the database (up to 1000 sequences) Tree Build a clustering or phylogenetic tree BLAST BLAST a flu sequence against the database Annotation Annotate flu genomic sequences FTP Retrieve database and sequence data through ftp Sample Searches Begin HA proteins of the H3 subtype Influenza A virus in US from 1998 to 2002. Sort the result first by host, and then by subtype and sequence length in the descending order. Complete genome sets of the H5N1 subtype Influenza A virus in human after 2000. New records in Entrez Publications on influenza viruses from the past 2 weeks Sequences from the NIAID Flu Project from the past week All influenza sequences updated in GenBank from the past week How to cite NCBI's Influenza Virus Resource Bao Y., P. Bolotov, D. Dernovoy, B. Kiryutin, L. Zaslavsky, T. Tatusova, J. Ostell, and D. Lipman. The Influenza Virus Resource at the National Center for Biotechnology Information. J. Virol. 2008 Jan;82(2):596-601. Our recent publications Zaslavsky L, et al. Visualization of large influenza virus sequence datasets using adaptively aggregated trees with sampling-based subscale representation. BMC Bioinformatics, 2008;9:237. Zaslavsky L, et al. Accelerating the neighbor-joining algorithm using the adaptive bucket data structure. Bioinformatics Research and Applications. Lecture Notes in Computer Science, Springer-Verlag, 2008;4983:122-133. More Zaslavsky L, et al. Multiresolution approaches to representation and visualization of large influenza virus sequence datasets. IEEE International Conference on Bioinformatics and Biomedicine. 2007. Bao Y, et al. The Influenza Virus Resource at the National Center for Biotechnology Information. Journal of Virology. 2008 Jan;82(2):596-601. Bao Y, et al. FLAN: a web server for influenza virus genome annotation. Nucleic Acids Research. 2007 Jul 1;35(Web Server issue):W280-4. Zaslavsky L, et al. An Adaptive Resolution Tree Visualization of Large Infuenza Virus Sequence Datasets. Bioinformatics Research and Applications. Lecture Notes in Computer Science, Springer-Verlag, 2007;4463:192-202. Ghedin E, et al. Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution. Nature. 2005 Oct 20;437(7062):1162-6. Holmes EC, et al. Whole-genome analysis of human influenza A virus reveals multiple persistent lineages and reassortment among recent H3N2 viruses. PLoS Biol. 2005 Sep;3(9):e300.

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