The Registry of Toxic Effects of Chemical Substances

Potassium hydroxide

RTECS #: TT2100000

CAS #: 1310-58-3

UPDATE: May 2008 MW: 56.11 MF: HKO


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. ACUTE TOXICITY DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. Caustic potash
  2. Hydroxyde de potassium (French)
  3. Kaliumhydroxid (German)
  4. Kaliumhydroxyde (Dutch)
  5. LYE
  6. Potassa
  1. Potasse caustique (French)
  2. Potassium hydrate
  3. Potassio (idrossido di) (Italian)
  4. Potassium hydroxide (ACGIH)
  5. Potassium (hydroxyde de) (French)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		1 mg/24 hour rinse moderate TXAPA9 32,239,1975
skin
guinea pig 		50 mg/24 hour severe TXAPA9 31,481,1975
skin
human 		50 mg/24 hour severe TXAPA9 31,481,1975
skin
rabbit 		50 mg/24 hour severe TXAPA9 31,481,1975


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis hamster ovary 12 mmol/L MUREAV 225,55,1989
cytogenetic analysis rat Ascites tumor 1,800 mg/kg GANNA2 54,155,1963


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 273 mg/kg N/R FAATDF 8,97,1987


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 2 mg/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
ARTODN 39,299,1978


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,326,1998
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg/m3, JAN1993
Occupational Exposure Limit - BELGIUM short term exposure limit 2 mg/m3, JAN1993
Occupational Exposure Limit - DENMARK ceiling concentration 2 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 2 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VLE 2 mg/m3, FEB2006
Occupational Exposure Limit - JAPAN Occupational Exposure Limit- continuous 2 mg/m3, APR2007
Occupational Exposure Limit - KOREA ceiling concentration 2 mg/m3, 2006
Occupational Exposure Limit - THE NETHERLANDS MAC- continuous 2 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND ceiling concentration 2 mg/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 2 mg/m3, JAN1999
Occupational Exposure Limit - SWEDEN time-weighted average 1 mg/m3;
short term exposure limit 2 mg/m3, (inhal. dust), JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg/m3, DEC2006
Occupational Exposure Limit - UNITED KINGDOM short term exposure limit 2 mg/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

ceiling concentration 2 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
ceiling concentration 2 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO POTASSIUM HYDROXIDE-air ceiling concentration 2 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 60440;
Number of Industries 340;
Total Number of Facilities 80,620;
Number of Occupations 181;
Total Number of Employees Exposed 1,081,553
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X3783;
Number of Industries 11;
Total Number of Facilities 543;
Number of Occupations 16;
Total Number of Employees Exposed 6,722;
Total Number of Female Employees Exposed 2,651
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 60440;
Number of Industries 346;
Total Number of Facilities 74,278;
Number of Occupations 221;
Total Number of Employees Exposed 1,959,889;
Total Number of Female Employees Exposed 797,390


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an industrial chemical
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9197
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Alkaline dusts, 7401


REFERENCES:

CODEN
REFERENCE
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP.
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used as an industrial chemical

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Human Data
   Primary Irritant

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