Welcome to the January 2009 Cell Migration Update, your one-stop resource for news, highlights and research on cell migration.
FEATURED ARTICLES
Specially written Editor's reviews of the hottest new articles
Dendritic cell migration: Coupling movement and antigen processing
Standfirst
The major histocompatibility complex class II-associated invariant chain (Ii) regulates dendritic cell movement by controlling myosin-II activity, thus providing a mechanism to coordinate antigen processing and migration.
Original research paper: Science 322, 1705-1710 (2008)
Neural Crest migration: Guided by contact
Standfirst
Contact inhibition of locomotion is important for the directional migration of neural crest cells and requires non-canonical Wnt signalling.
Original research paper: Nature 456, 957-961 (2008)
RESEARCH HIGHLIGHTS
Synopses of important recent articles
Metastasis: Moved to act
Standfirst
A recent study has shown that differential activation of the small GTPases Rac and Rho determines whether a tumour cell uses an amoeboid-like or a mesenchymal-like type of movement.
Nature Reviews Cancer 9, 3 (2009)
Cytoskeleton: Invading forces
Standfirst
The Enabled (Ena)/vasodilator-stimulated phosphoprotein (Vasp) family member MENA, which binds to and regulates actin dynamics, has been shown to promote invasion and metastasis of breast cancer cells.
Nature Reviews Cancer 9, 12 - 13 (2009)
NEWS
The latest news selected from the CMC, Nature News and journals from the Nature family
Chemosensors: Specificity for kinases.
Villin structure: F-actin crosslinking revealed.
Imaging advances provide immune-cell breakthroughs
Standfirst
Microscopy tracks living cells as they move through the body.
CELL MIGRATION KNOWLEDGEBASE
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CONSORTIUM ACTIVITIES
Find out more about the Consortium activities, and the latest Consortium Updates.
