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- Landmark Council Session Spotlights “Real World” Trials
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December 21, 2006
Science Update
Principal investigators of NIMH's four large-scale clinical trials presented study results and their implications at the National Advisory Mental Health Council meeting on September 15, 2006.
- Odds of Beating Depression Diminish as Additional Treatment Strategies are Needed
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November 1, 2006
Science Update
An overall assessment of the nation's largest real-world study of treatment-resistant depression suggests that a patient with persistent depression can get well after trying several treatment strategies, but his or her odds of beating the depression diminish as additional treatment strategies are needed.
- Subsequent Treatment Strategies for Persistent Depression Yield Modest Results
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September 1, 2006
Science Update
Patients with treatment-resistant depression had a modest chance of becoming symptom-free when they tried different treatment strategies after two or three failed treatments, according to results from the nation's largest real-world study of depression.
- College Women at Risk for Eating Disorder May Benefit From Online Intervention
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August 7, 2006
Press Release
A long-term, large-scale study has found that an Internet-based intervention program may prevent some high risk, college-age women from developing an eating disorder.
- Targeted Therapy Halves Suicide Attempts in Borderline Personality Disorder
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July 3, 2006
Science Update
Dialectical Behavior Therapy (DBT) reduced suicide attempts by half compared with other types of psychotherapy available in the community in patients with borderline personality disorder, an NIMH-funded study has found.
- Properly Timed Light, Melatonin Lift Winter Depression by Syncing Rhythms
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May 1, 2006
Science Update
Most Seasonal Affective Disorder (SAD) symptoms stem from daily body rhythms that have gone out-of-sync with the sun, a NIMH-funded study has found.
- Studies Offer New Information About Treatment Choices for Schizophrenia — Phase 2 Results
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April 1, 2006
Science Update
A national clinical trial comparing clozapine with other new-generation antipsychotic medications for the treatment of chronic schizophrenia has shown that people who switched to clozapine from their first medication because it failed to manage symptoms adequately were twice as likely to continue treatment as patients who switched to other antipsychotic medications.
- New Strategies Help Depressed Patients Become Symptom-Free
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March 23, 2006
Press Release
Results of the nation’s largest depression study show that one in three depressed patients who previously did not achieve remission using an antidepressant became symptom-free with the help of an additional medication and one in four achieved remission after switching to a different antidepressant.
- Maintenance Treatment Prevents Recurrence in Older Adults with Single-Episode Depression
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March 16, 2006
Press Release
People age 70 and older who continued taking the antidepressant that helped them to initially recover from their first episode of depression were 60 percent less likely to experience a new episode of depression over a two-year study period than those who stopped taking the medication, according to a study funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.
- Early Findings from Largest NIMH-Funded Research Program on Bipolar Disorder Begin to Build Evidence-Base on Best Treatment Options
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February 1, 2006
Science Update
Findings from an NIMH research program on bipolar disorder provide much needed long-term data on the chronic, recurrent course of the disorder, and begin the work of building an evidence-base on the best treatments for those with the disorder.