Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors
A total of 295 patients will be accrued for this study.
This is a multicenter study. Patients are assigned to 1 of 6 treatment regimens according to tumor histology, stage of disease, and response to treatment.
Treatment continues in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed periodically for at least 3 years.
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U.S.A. |
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Alabama |
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Birmingham |
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| Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham |
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| Clinical Trials Office - Lurleen Wallace Comprehensive Cancer | |
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Arizona |
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Phoenix |
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| Phoenix Children's Hospital |
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| Jessica Boklan | |
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Tucson |
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| Arizona Cancer Center at University of Arizona Health Sciences Center |
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| Clinical Trials Office - Arizona Cancer Center at University of Arizona Health Sciences Center | |
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Arkansas |
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Little Rock |
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| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences |
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| Clinical Trial Office - Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | |
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California |
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Downey |
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| Southern California Permanente Medical Group |
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| Robert Cooper | |
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Loma Linda |
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| Loma Linda University Cancer Institute at Loma Linda University Medical Center |
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| Clinical Trials Office - Loma Linda University Cancer Institute | |
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Long Beach |
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| Jonathan Jaques Children's Cancer Center at Miller Children's Hospital |
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| Jerry Finklestein | |
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Los Angeles |
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| Childrens Hospital Los Angeles |
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| Leo Mascarenhas | |
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Madera |
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| Children's Hospital Central California |
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| Vonda Crouse | |
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Orange |
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| Children's Hospital of Orange County |
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| Violet Shen | |
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Sacramento |
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| Kaiser Permanente Medical Center - Oakland |
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| Vincent Kiley | |
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San Francisco |
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| UCSF Helen Diller Family Comprehensive Cancer Center |
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| Clinical Trials Office - UCSF Helen Diller Family Comprehensive Cancer Center | |
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Stanford |
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| Stanford Cancer Center |
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| Clinical Trials Office - Stanford Cancer Center | |
| Email:
cctoffice@stanford.edu |
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Colorado |
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Aurora |
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| Children's Hospital Center for Cancer and Blood Disorders |
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| Kelly Maloney | |
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Connecticut |
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Farmington |
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| Carole and Ray Neag Comprehensive Cancer Center at the
University of Connecticut Health Center |
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| Clinical Trials Office - Carole and Ray Neag Comprehensive Cancer Center | |
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Delaware |
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Wilmington |
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| Alfred I. duPont Hospital for Children |
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| Clinical Trials Office - Alfred I. duPont Hospital for Children | |
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District of Columbia |
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Washington |
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| Children's National Medical Center |
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| Clinical Trials Office - Children's National Medical Center | |
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| Walter Reed Army Medical Center |
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| Clinical Trials Office - Walter Reed Army Medical Center | |
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Florida |
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Fort Lauderdale |
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| Broward General Medical Center Cancer Center |
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| Clinical Trials Office - Broward General Medical Center Cancer Center | |
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Fort Myers |
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| Lee Cancer Care of Lee Memorial Health System |
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| Clinical Trials Office - Lee Cancer Care of Lee Memorial Health System | |
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Gainesville |
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| University of Florida Shands Cancer Center |
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| Clinical Trials Office - University of Florida Shands Cancer Center | |
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Hollywood |
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| Memorial Cancer Institute at Memorial Regional Hospital |
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| Clinical Trials Office - Memorial Cancer Institute | |
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Jacksonville |
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| Nemours Children's Clinic |
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| Eric Sandler | |
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Miami |
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| Baptist-South Miami Regional Cancer Program |
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| Doured Daghistani | |
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| Miami Children's Hospital |
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| Enrique Escalon | |
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Orlando |
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| M.D. Anderson Cancer Center at Orlando |
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| Contact Person | Ph: | 407-648-3800 | | 800-648-3818 |
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| Nemours Children's Clinic - Orlando |
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| Contact Person | |
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Pensacola |
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| Sacred Heart Cancer Center at Sacred Heart Hospital |
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| Clinical Trials Office - Sacred Heart Cancer Center | |
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St. Petersburg |
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| All Children's Hospital |
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| Jerry Barbosa | |
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Tampa |
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| St. Joseph's Cancer Institute at St. Joseph's Hospital |
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| Clinical Trials Office - St. Joseph's Cancer Institute | |
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West Palm Beach |
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| Kaplan Cancer Center at St. Mary's Medical Center |
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| Narayana Gowda | |
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Georgia |
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Atlanta |
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| Winship Cancer Institute of Emory University |
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| Howard Katzenstein | |
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Savannah |
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| Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center |
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| Clinical Trials Office - Curtis and Elizabeth Anderson Cancer Institute | |
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Hawaii |
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Honolulu |
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| Cancer Research Center of Hawaii |
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| Clinical Trials Office - Cancer Research Center of Hawaii | |
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Illinois |
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Chicago |
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| Children's Memorial Hospital - Chicago |
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| David Walterhouse | |
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| University of Chicago Cancer Research Center |
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| Clinical Trials Office - University of Chicago Cancer Research Center | |
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Oak Lawn |
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| Advocate Christ Medical Center |
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| Sharad Salvi | |
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Park Ridge |
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| Advocate Lutheran General Cancer Care Center |
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| Clinical Trials Office - Advocate Lutheran General Cancer Care Center | |
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Peoria |
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| Saint Jude Midwest Affiliate |
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| Stephen Smith | |
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Springfield |
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| Simmons Cooper Cancer Institute |
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| Clinical Trials Office - Simmons Cooper Cancer Institute | |
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Indiana |
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Indianapolis |
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| Indiana University Melvin and Bren Simon Cancer Center |
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| Clinical Trials Office - Indiana University Cancer Center | |
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| St. Vincent Indianapolis Hospital |
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| Clinical Trials Office - St. Vincent Indianapolis Hospital | |
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Iowa |
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Des Moines |
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| Blank Children's Hospital |
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| Clinical Trials Office - Blank Children's Hospital | |
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Iowa City |
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| Holden Comprehensive Cancer Center at University of Iowa |
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| Cancer Information Service | |
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Kansas |
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Kansas City |
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| Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center |
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| Clinical Trials Office - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center | |
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Kentucky |
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Lexington |
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| Lucille P. Markey Cancer Center at University of Kentucky |
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| Clinical Trials Office - Markey Cancer Center at University of Kentucky Chandler Medical Center | |
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Louisville |
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| Kosair Children's Hospital |
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| Clinical Trials Office - Kosair Children's Hospital | |
| Email:
CancerResource@nortonhealthcare.org |
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Louisiana |
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Alexandria |
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| Tulane Cancer Center Office of Clinical Research |
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| Clinical Trials Office - Tulane Cancer Center | |
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Maine |
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Scarborough |
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| Maine Children's Cancer Program at Barbara Bush Children's Hospital |
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| Eric Larsen | |
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Maryland |
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Baltimore |
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| Alvin and Lois Lapidus Cancer Institute at Sinai Hospital |
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| Joseph Wiley | |
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| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
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| Clinical Trials Office - Sidney Kimmel Comprehensive Cancer Center at John Hopkins | |
| Email:
jhcccro@jhmi.edu |
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Massachusetts |
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Boston |
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| Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute |
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| Holcombe Grier | |
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| Massachusetts General Hospital |
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| Clinical Trials Office - Massachusetts General Hospital | |
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Michigan |
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Ann Arbor |
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| C.S. Mott Children's Hospital at University of Michigan Medical Center |
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| Clinical Trials Office - C.S. Mott Children's Hospital | |
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Detroit |
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| Barbara Ann Karmanos Cancer Institute |
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| Clinical Trials Office - Barbara Ann Karmanos Cancer Institute | |
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Grand Rapids |
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| Butterworth Hospital at Spectrum Health |
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| David Dickens | |
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Grosse Pointe Woods |
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| Van Elslander Cancer Center at St. John Hospital and Medical Center |
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| Clincial Trials Office - Van Elslander Cancer Center at St. John Hospital and Medical Center | |
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Kalamazoo |
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| CCOP - Kalamazoo |
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| Leonard Mattano, Jr. | |
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Lansing |
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| Breslin Cancer Center at Ingham Regional Medical Center |
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| Clinical Trials Office - Breslin Cancer Center at Ingham Regional Medical Center | |
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Minnesota |
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Minneapolis |
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| Children's Hospitals and Clinics of Minnesota - Minneapolis |
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| Clinical Trials Office - Children's Hospitals and Clinics of Minnesota | |
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Rochester |
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| Mayo Clinic Cancer Center |
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| Clinical Trials Office - All Mayo Clinic Locations | |
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Mississippi |
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Jackson |
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| University of Mississippi Cancer Clinic |
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| Gail Megason | |
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Missouri |
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Kansas City |
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| Children's Mercy Hospital |
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| Maxine Hetherington | |
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St. Louis |
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| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis |
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| Robert Hayashi | |
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Nebraska |
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Omaha |
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| Children's Hospital |
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| Minnie Abromowitch | |
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Nevada |
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Las Vegas |
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| Sunrise Hospital and Medical Center |
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| Jonathan Bernstein | |
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New Hampshire |
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Lebanon |
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| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center |
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| Clinical Trials Office - Norris Cotton Cancer Center | |
| Email:
cancerhelp@dartmouth.edu |
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New Jersey |
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Hackensack |
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| Hackensack University Medical Center Cancer Center |
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| Clinical Trials Office - Hackensack University Medical Center Cancer Center | |
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Morristown |
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| Overlook Hospital |
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| Hazem Mahmoud | |
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New Brunswick |
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| Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School |
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| Clinical Trials Office - Cancer Institute of New Jersey | |
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Newark |
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| Newark Beth Israel Medical Center |
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| Clinical Trials Office - Newark Beth Israel Medical Center | |
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Paterson |
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| St. Joseph's Hospital and Medical Center |
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| Mary Ann Bonilla | |
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New Mexico |
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Albuquerque |
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| University of New Mexico Cancer Center |
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| Clinical Trials Office - University of New Mexico Cancer Center | |
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New York |
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Buffalo |
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| Roswell Park Cancer Institute |
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| Clinical Trials Office - Roswell Park Cancer Institute | |
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New Hyde Park |
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| Schneider Children's Hospital |
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| Arlene Redner | |
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New York |
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| Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center |
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| Clinical Trials Office - Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center | |
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| New York Weill Cornell Cancer Center at Cornell University |
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| Clinical Trials Office - New York Weill Cornell Cancer Center at Cornell University | |
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| NYU Cancer Institute at New York University Medical Center |
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| Elizabeth Raetz | |
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Rochester |
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| James P. Wilmot Cancer Center at University of Rochester Medical Center |
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| Barbara Asselin | |
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Stony Brook |
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| Stony Brook University Cancer Center |
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| Clinical Trials Office - Stony Brook University Cancer Center | |
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Syracuse |
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| SUNY Upstate Medical University Hospital |
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| Clinical Trials Office - SUNY Upstate Medical University Hospital | |
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Valhalla |
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| New York Medical College |
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| Fevzi Ozkaynak | |
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North Carolina |
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Asheville |
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| Mission Hospitals - Memorial Campus |
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| Clinical Trials Office - Mission Hospitals - Memorial Campus | |
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Chapel Hill |
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| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill |
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| Clinical Trials Office - Lineberger Comprehensive Cancer Center | Ph: | 877-668-0683; 919-966-4432 | | |
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Charlotte |
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| Blumenthal Cancer Center at Carolinas Medical Center |
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| Clinical Trials Office - Blumenthal Cancer Center at Carolinas Medical Center | |
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| Presbyterian Cancer Center at Presbyterian Hospital |
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| Clinical Trials Office - Presbyterian Cancer Center at Presbyterian Hospital | |
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Durham |
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| Duke Comprehensive Cancer Center |
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| Clinical Trials Office - Duke Comprehensive Cancer Center | |
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Greenville |
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| Leo W. Jenkins Cancer Center at ECU Medical School |
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| Clinical Trials Office - Leo W. Jenkins Cancer Center at ECU Medical School | |
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Winston-Salem |
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| Wake Forest University Comprehensive Cancer Center |
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| Clinical Trials Office - Wake Forest University Comprehensive Cancer Center | |
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Ohio |
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Akron |
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| Akron Children's Hospital |
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| Clinical Trials Office - Akron Children's Hospital | |
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Cincinnati |
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| Cincinnati Children's Hospital Medical Center |
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| Clinical Trials Office - Cincinnati Children's Hospital Medical Center | |
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Cleveland |
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| Cleveland Clinic Taussig Cancer Center |
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| Clinical Trials Office - Cleveland Clinic Taussig Cancer Center | |
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| Rainbow Babies and Children's Hospital |
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| Susan Wiersma | |
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Columbus |
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| Nationwide Children's Hospital |
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| Amanda Termuhlen | |
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Dayton |
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| Children's Medical Center - Dayton |
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| Emmett Broxson | |
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Toledo |
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| Toledo Hospital |
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| Clinical Trials Office - Toledo Hospital | |
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Oklahoma |
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Oklahoma City |
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| Oklahoma University Cancer Institute |
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| Rene McNall-Knapp | |
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Tulsa |
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| Natalie Warren Bryant Cancer Center at St. Francis Hospital |
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| Gregory Kirkpatrick | |
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Oregon |
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Portland |
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| Legacy Emanuel Hospital and Health Center and Children's Hospital |
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| Clinical Trials Office - Legacy Emanuel Hospital and Health Center and Children's Hospital | |
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Pennsylvania |
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Bethlehem |
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| Lehigh Valley Hospital - Muhlenberg |
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| Philip Monteleone | |
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Danville |
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| Geisinger Cancer Institute at Geisinger Health |
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| Clinical Trials Office - Geisinger Cancer Institute | |
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|
Hershey |
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| Penn State Cancer Institute at Milton S. Hershey Medical Center |
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| Clinical Trials Office - Penn State Cancer Institute at Milton S. Hershey Medical Center | |
| Email:
CTO@hmc.psu.edu |
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Philadelphia |
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| Children's Hospital of Philadelphia |
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| Peter Adamson | |
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| St. Christopher's Hospital for Children |
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| Clinical Trials Office - St. Christopher's Hospital for Children | |
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Pittsburgh |
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| Children's Hospital of Pittsburgh |
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| Clinical Trials Office - Children's Hospital of Pittsburgh | |
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Rhode Island |
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|
Providence |
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|
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| Rhode Island Hospital Comprehensive Cancer Center |
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| Clinical Trials Office - Rhode Island Hospital Comprehensive Cancer Center | |
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South Carolina |
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Charleston |
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| Hollings Cancer Center at Medical University of South Carolina |
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| Clinical Trials Office - Hollings Cancer Center at Medical University of South Carolina | |
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Columbia |
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| Palmetto Health South Carolina Cancer Center |
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| Clinical Trials Office - Palmetto Health South Carolina Cancer Center | |
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Greenville |
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| Greenville Hospital Cancer Center |
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| Clinical Trials Office - Greenville Hospital Cancer Center | |
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South Dakota |
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Sioux Falls |
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| Sanford Cancer Center at Sanford USD Medical Center |
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| Clinical Trials Office - Sanford Cancer Center | |
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Tennessee |
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Chattanooga |
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| T.C. Thompson Children's Hospital |
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| Manoo Bhakta | |
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Knoxville |
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| East Tennessee Children's Hospital |
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| Ray Pais | |
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Memphis |
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| St. Jude Children's Research Hospital |
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| Clinical Trials Office - St. Jude Children's Research Hospital | |
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Nashville |
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| Vanderbilt-Ingram Cancer Center |
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| Clinical Trials Office - Vanderbilt-Ingram Cancer Center | |
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Texas |
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Amarillo |
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| Texas Tech University Health Sciences Center School of Medicine - Amarillo |
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| Curtis Turner | |
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Austin |
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| Dell Children's Medical Center of Central Texas |
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| Clinical Trials Office - Dell Children's Medical Center of Central Texas | |
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Corpus Christi |
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| Driscoll Children's Hospital |
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| Clinical Trials Office - Driscoll Children's Hospital | |
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Dallas |
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| Medical City Dallas Hospital |
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| Carl Lenarsky | |
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| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas |
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| Clinical Trials Office - Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | Ph: | 866-460-4673; 214-648-7097 | | |
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Fort Worth |
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| Cook Children's Medical Center - Fort Worth |
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| Clinical Trials Office - Cook's Children's Medical Center | |
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San Antonio |
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| Methodist Children's Hospital of South Texas |
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| Donna Wall | |
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| University of Texas Health Science Center at San Antonio |
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| Paul Thomas | |
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Temple |
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| CCOP - Scott and White Hospital |
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| Arlynn Mulne | |
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Utah |
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Salt Lake City |
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| Primary Children's Medical Center |
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| Phillip Barnette | |
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Vermont |
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Burlington |
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| Fletcher Allen Health Care - University Health Center Campus |
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| Clinical Trials Office - Fletcher Allen Health Care | |
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Virginia |
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Falls Church |
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| Inova Fairfax Hospital |
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| Clinical Trials Office - Inova Fairfax Hospital | |
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Norfolk |
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| Children's Hospital of The King's Daughters |
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| Eric Lowe | |
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Roanoke |
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| Carilion Medical Center for Children at Roanoke Community Hospital |
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| Joan Fisher | |
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Washington |
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Seattle |
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| Children's Hospital and Regional Medical Center - Seattle |
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| Douglas Hawkins | |
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Spokane |
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| Providence Cancer Center at Sacred Heart Medical Center |
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| Judy Felgenhauer | |
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Tacoma |
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| Mary Bridge Children's Hospital and Health Center - Tacoma |
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| Ronald Louie | |
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West Virginia |
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Charleston |
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| West Virginia University Health Sciences Center - Charleston |
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| Elizabeth Kurczynski | |
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Wisconsin |
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|
Marshfield |
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| Marshfield Clinic - Marshfield Center |
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| Clinical Trials Office - Marshfield Clinic - Marshfield Center | Ph: | 800-782-1581 ext. 94457 | | |
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Milwaukee |
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| Midwest Children's Cancer Center at Children's Hospital of Wisconsin |
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| Bruce Camitta | |
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Australia |
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New South Wales |
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Newcastle |
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| John Hunter Hospital |
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| Elizabeth Hesketh | |
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Randwick |
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| Prince of Wales Private Hospital |
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| Draga Barbaric | |
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South Australia |
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North Adelaide |
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| Women's and Children's Hospital |
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| Maria Kirby | |
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Western Australia |
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Perth |
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| Princess Margaret Hospital for Children |
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| Catherine Cole | |
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Canada |
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Quebec |
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|
|
| Centre Hospitalier Universitaire de Quebec |
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| Yvan Samson | |
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Alberta |
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Calgary |
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|
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| Alberta Children's Hospital |
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| Douglas Strother | |
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Edmonton |
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| University of Alberta Hospital |
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| Sunil Desai | |
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British Columbia |
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Vancouver |
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|
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| Children's & Women's Hospital of British Columbia |
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| Mason Bond | |
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Manitoba |
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|
Winnipeg |
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|
|
| CancerCare Manitoba |
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| Rochelle Yanofsky | |
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Nova Scotia |
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|
Halifax |
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|
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| IWK Health Centre |
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| Margaret Yhap | |
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Ontario |
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Hamilton |
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|
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| McMaster Children's Hospital at Hamilton Health Sciences |
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| Carol Portwine | |
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|
Kingston |
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|
| Cancer Centre of Southeastern Ontario at Kingston General Hospital |
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| Mariana Silva | |
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London |
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| Children's Hospital of Western Ontario |
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| A. Cairney | |
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|
Ottawa |
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|
| Children's Hospital of Eastern Ontario |
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| Jacqueline Halton | |
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Toronto |
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| Hospital for Sick Children |
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| Ronald Grant | |
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Quebec |
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Montreal |
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|
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| Hopital Sainte Justine |
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| Albert Moghrabi | |
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| Montreal Children's Hospital at McGill University Health Center |
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| Sharon Abish | |
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Saskatchewan |
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Saskatoon |
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|
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| Saskatoon Cancer Centre at the University of Saskatchewan |
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| Kaiser Ali | |
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New Zealand |
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Auckland |
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|
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| Starship Children's Health |
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| Lochie Teague | |
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Puerto Rico |
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|
Santurce |
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|
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| San Jorge Children's Hospital |
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| Luis Clavell | |
|