Susceptibility of North American Ducks and Gulls to H5N1 Highly Pathogenic Avian Influenza Viruses
Justin D. Brown,* David E. Stallknecht,* Joan R. Beck,† David L. Suarez,† and David E. Swayne†
*College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA; and †Southeast Poultry
Research Laboratory, Athens, Georgia, USA
Vol. 12, No. 11 • November 2006
| Table 1. Morbidity, mortality, and virus isolation data from 5 species of ducks and laughing gulls* intranasally inoculated with 2 different H5N1 HPAI viruses† | ||||||||
| Virus/Host | No. sick/total (‡) |
No. dead/total (§) |
Virus isolation (oral swab) |
Virus isolation (cloacal swab) |
||||
Prevalence, no. positive/total |
Duration, days |
AMT¶ (log10 EID50/mL) |
Prevalence, no. positive/total |
Duration, days |
AMT (log10 EID50/mL) |
|||
| Mongolia/05 | ||||||||
| BWT | 0/3 |
0/3 |
3/3 |
2 |
3.8 |
1/3 |
1 |
1.0 |
| RD | 0/3 |
0/3 |
3/3 |
1–4 |
2.8 |
2/3 |
1 |
1.2 |
| WD | 2/3 (5) |
2/3 (7,8) |
3/3 |
4–6 |
4.6 |
2/3 |
2,3 |
3.8 |
| MD | 0/3 |
0/3 |
3/3 (1) |
1–3 |
3.1 |
1/3 (1) |
1 |
1.0 |
| NP | 0/3 |
0/3 |
3/3 |
1–2 |
1.5 |
1/3 |
1 |
1.0 |
| LG | 3/3 (2–5) |
2/3 (7,8) |
3/3 |
7–8 |
4.2 |
3/3 |
4–7 |
2.6 |
| Anyang/01 | ||||||||
| BWT | 0/3 |
0/3 |
2/3 |
1,2 |
2.0 |
0/3 |
– |
– |
| RD | 0/3 |
0/3 |
2/3 |
4 |
4.0 |
0/3 |
– |
– |
| WD | 2/3 (6) |
1/3 (8) |
3/3 |
7 |
5.0 |
2/3 |
4,5 |
2.8 |
| MD | 0/3 |
0/3 |
3/3 |
1–2 |
2.1 |
1/3 |
1 |
1.0 |
| NP | 0/3 |
0/3 |
2/3 |
1,4 |
1.1 |
0/3 |
– |
– |
| LG | 3/3 (3–5) |
2/3 (9–10) |
3/3 |
6–10 |
5.0 |
3/3 |
3–6 |
2.0 |
| *Intranasally sham-inoculated control birds for each avian species lacked clinical, serologic, virologic, and pathologic evidence of avian influenza virus infection. | ||||||||
| †HPAI, highly pathogenic avian influenza; BWT, blue-winged teal; RD, redhead; WD, wood duck; MD, mallard; NP, northern pintail, LG, laughing gull; Mongolia/05, A/Whooper Swan/Mongolia/244/05; Anyang/01, A/Duck Meat/Anyang/01. | ||||||||
| ‡No. in parentheses indicates the first day postinoculation that clinical disease was apparent. | ||||||||
| §No. in parentheses indicates day of death. | ||||||||
| ¶Average maximum titer (AMT) is the average peak titer for birds that shed virus (log10 50% embryo infective dose/mL). | ||||||||
This page posted October 13, 2006
This page last reviewed November 30, 2006
