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Meningococcal Disease (Neisseria meningitidis)
1997 Case Definition
Clinical description
Meningococcal disease manifests most commonly as
meningitis and/or meningococcemia that may progress rapidly to
purpura fulminans, shock, and death. However, other manifestations
might be observed.
Laboratory criteria for diagnosis
-
Isolation of Neisseria meningitidis from
a normally sterile site (e.g., blood or cerebrospinal fluid
[CSF] or, less commonly, joint, pleural, or pericardial fluid)
Case classification
Probable: a case
with a positive antigen test in CSF or clinical purpura fulminans
in the absence of a positive blood culture
Confirmed: a clinically compatible case
that is laboratory confirmed
Comment
Positive antigen test results from urine or serum
samples are unreliable for diagnosing meningococcal disease.
See also:
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