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Hepatitis, Viral
1990 Case Definition
Clinical case definition
An illness with a) discrete onset of symptoms and b) jaundice
or elevated serum aminotransferase levels
Laboratory criteria for diagnosis
- Hepatitis A: IgM
anti-HAV-positive
- Hepatitis B: IgM anti-HBc-positive (if
done) or HBsAg-positive, and IgM anti-HAV-negative (if done)
- Non-A, Non-B Hepatitis:
- IgM anti-HAV-negative, and
- IgM anti-HBc-negative (if done) or HBsAg-negative,
and
- Serum aminotransferase levels greater than
2 1/2 times the upper limit of normal
- Delta Hepatitis: HBsAg- or IgM anti-HBc-positive
and anti-HDV-positive
Case classification
Confirmed: a case that
meets the clinical case definition and is laboratory confirmed
Comment
A serologic test for IgG antibody to the recently described
hepatitis C virus is available, and many cases of non-A, non-B hepatitis
may be demonstrated to be due to infection with the hepatitis C virus.
With this assay, however, a prolonged interval between onset of disease
and detection of antibody may occur. Until a more specific test for acute
hepatitis C becomes available, these cases should be reported as non-A,
non-B hepatitis. Chronic carriage or chronic hepatitis should not be
reported.
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