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Acquired Immunodeficiency Syndrome (AIDS)
1993 Case Definition
Case definition
CDC has expanded the acquired immunodeficiency syndrome
(AIDS) surveillance case definition to include all human immunodeficiency
virus (HIV)-infected adolescents and adults aged greater than or equal
to 13 years who have either a) less than 200 CD4positive T-lymphocytes/uL;
b) a CD4positive T-lymphocyte percentage of total lymphocytes of less than
14%; or c) any of the following three clinical conditions: pulmonary tuberculosis,
recurrent pneumonia, or invasive cervical cancer. The expanded definition
retains the 23 clinical conditions in the AIDS surveillance case definition
published in 1987. (See publication (1) in Publications List in this section
for complete information referring to this case definition.)
The AIDS surveillance case definition for children aged
less than 13 years has not changed and retains the clinical conditions
listed in the AIDS surveillance case definition published in 1987.
However, definitions for HIV encephalopathy, HIV wasting syndrome,
and HIV infection in children have been revised and the 1987 definition
has been updated. (See Publication (2) in Publications List for complete
information pertaining to this case definition.)
Laboratory criteria for diagnosis
See Publication (1) in Publications List.
Case classification
CDC has revised the classification system for HIV infection
to emphasize the clinical importance of the CD4positive T-lymphocyte count
in the categorization of HIV-related clinical conditions. This classification
system replaces the system published by CDC in 1986. (See Publication (1)
in Publications List for complete information pertaining to this case definition.)
Publications list
- CDC. 1993 Revised classification system for HIV infection
and expanded surveillance case definition for AIDS among adolescents
and adults. MMWR 1992;41(No. RR-17).
- CDC. 1994 Revised classification system for human
immunodeficiency virus infection in children less than 13 years of
age. MMWR 1994;43(No. RR-12).
- CDC. Interpretation and use of the Western blot assay
for serodiagnosis of human immunodeficiency virus type-1 infection. MMWR 1989;38(No.
S-7).
- Revision of the CDC surveillance case definition for
acquired immunodeficiency syndrome. MMWR 1987;36(suppl:)1-15s.
See also:
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