Volume 10, Number 12, December 2004

Experimental Everglades Virus Infection of Cotton Rats (Sigmodon hispidus)

Lark L. Coffey,* Anne-Sophie Carrara,* Slobodan Paessler,* Michelle L. Haynie,† Robert D. Bradley,† Robert B. Tesh,* and Scott C. Weaver*
*University of Texas Medical Branch, Galveston, Texas, USA; and †Texas Tech University, Lubbock, Texas, USA

Figure 4. Brainstem section of sham-inoculated control rat, showing the absence of an inflammatory response (A). Vascular and perivascular infiltration of mononuclear cells within the brainstem of a Florida cotton rat 7 days after infection with 3.2 log₁₀ PFU/mL EVEV strain FE4-71k; inset enlarged to show cell infiltration (B). Cortex of cotton rat 5 weeks after infection, showing absence of inflammatory response (C). Animals in panels A and B were anesthetized with pentobarbital and perfused with phosphate-buffered saline intracardially. The rat in panel C was not perfused.

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This page last reviewed November 10, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
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