Table 2. Nucleotide mutations in sequences of the E gene of 22 West Nile virus isolates obtained during 2001 and 2002 compared to WN-NY99^a

Strain

Envelope (1503 ntds)

969

1038

1065

1071

1118 (E51)

1137

1179 (E71)

1192 (E76)

1293

1356

1377

1442 (E159)

1443

1554

1557

1581

1728

1830

2094

2154

2190

2392 (E476)

2400

2466

WN-NY99 (AF196835)

C

U

C

U

C (Ala)

C

A (Lys)

A (Thr)

C

C

C

U (Val)

U

T

C

T

A

T

A

U

U

G (Ala)

U

C

Harris Co., TX (AY185906)

C

A
(Thr)

U

Harris Co., TX (AY185907)

U

U

C

U

Nueces Co., TX - 1

U

C

C

U

Nueces Co., TX - 2

U
(Val)

U

U

C

U

Gregg Co., TX

C

C

U

Tarrant Co., TX

C

C

U

Wichita Co., TX

C

U

Randall Co., TX

U

C
(Asn)

C

U

El Paso Co., TX

C

U

Illinois - 1

C

U

Illinois - 2

C

U

C

C

U

Alabama - 1

C

U

Alabama -2

C

T

U

Colorado

C

G

U

Louisiana

Galveston Co., TX-1 (AY185914)

U

G
(Ala)

U

C

C

Galveston Co., TX-2 (AY185913)

U

G

U

C

C

Galveston Co., TX-3

U

G

U

C

C

C

Jefferson Co., TX - 1

U

G

U

C

C

Jefferson Co., TX - 2

U

C

G

U

C

C

Jefferson Co., TX - 3

U

G

U

C

C

Orange Co., TX

U

C

G

U

C

C

*Nucleotide (nt) numbers correspond to those of WN-NY99 (GenBank accession no. AF196835); in brackets for individual residues are the deduced amino acid changes.f