| Agent Name |
Carbonyl fluoride |
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| CAS Number |
353-50-4 |
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| Formula |
C-F2-O |
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| Major Category |
Toxic Gases & Vapors |
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| Synonyms |
Carbon difluoride oxide; Carbon fluoride oxide (COF2); Carbon oxyfluoride (COF2); Carbonic difluoride; Carbonyl difluoride; Carbonyl fluoride; Carbonyl oxyfluoride; Difluoroformaldehyde; Difluorooxomethane; Fluophosgene; Fluoroformyl fluoride; Fluorophosgene; [ChemIDplus] UN2417 |
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| Category |
Acid Halides |
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| Description |
Colorless gas with a pungent and very irritating odor; Note: Shipped as a liquefied compressed gas; [NIOSH] |
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| Sources/Uses |
Used in organic synthesis; generated from the thermal degradation of fluoropolymers, e.g., polytetrafluoroethylene (PTFE) and polyfluoroethylenepropylene; [ACGIH] |
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| Comments |
Liquid is a severe skin irritant; [CHRIS] Toxic effects from the liberation of fluoride by hydrolysis; causes pulmonary edema in animals exposed to lethal concentrations and liver and kidney damage in subchronic studies; "Critical Effects" are irritation; bone; fluorosis. [ACGIH] Possible frostbite from contact with liquid; [NIOSH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TIH |
Yes |
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| TLV (ACGIH) |
2 ppm |
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| STEL (ACGIH) |
5 ppm |
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| Lethal Concentration |
LC50 (rats) = 360 ppm/1h |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Adverse Effects |
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| Toxic Pneumonitis |
Yes |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CARBONYL DIFLUORIDE
|
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