| Agent Name |
Captan |
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| CAS Number |
133-06-2 |
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| Formula |
C9-H8-Cl3-N-O2-S |
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| Major Category |
Pesticides |
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| Synonyms |
N-Trichloromethylthio-4-cyclohexane-1,2-dicarboximide; Vancide 89; Dangard; Merpan; Orthocide-406; SR-406; [Marks, p. 268] Agrox; Captal; Captec; Captol; Captonex; Clomitane; Merpan; Meteoro; Orthocide; Phytocape; Sepicap; Sorene; Vancide 89; [EXTOXNET] |
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| Category |
Fungicides |
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| Description |
Odorless, white, crystalline powder. [fungicide] [Note: Commercial product is a yellow powder with a pungent odor.]; [NIOSH] |
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| Sources/Uses |
The thiophthalimides are widely used fungicides on seeds, field crops, and stored produce; [EPA Pesticides] Captan is also used as a biocide in paints, polishes, shampoos, and cosmetics. [Kanerva, p. 1134] No longer used as a fungicide in hair-care products; [Kanerva, p. 966] |
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| Comments |
The thiophthalimides include captan, captafol and folpet; no systemic poisonings in humans have been reported; [EPA Pesticides] Captan is an agricultural fungicide that has caused occupational allergic contact dermatitis usually after airborne exposure. [Marks, p. 267] Allergic contact dermatitis also reported in hairdressers, painters, polishers, and varnishers; [Kanerva, p. 1134] In high-dose reproductive animal studies, captan causes testicular damage and fetal losses. It is a possible teratogen. [Frazier, p. 232-4] |
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| Restricted |
Most uses on food crops were cancelled by the EPA in 1989 [EXTOXNET] |
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| Reference Link |
EXTOXNET - Captan |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
5 mg/m3, inhalable fraction |
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| Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
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| Adverse Effects |
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| Skin Sensitizer |
Yes |
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| Reproductive Toxin |
Yes |
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| IARC Carcinogen |
Not Classifiable |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: CAPTAN
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