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Agent Name Chloroacetone
CAS Number 78-95-5
Formula C3-H5-Cl-O
Major Category Toxic Gases & Vapors
Synonyms 1-Chloro-2-ketopropane; 1-Chloro-2-oxopropane; 1-Chloro-2-propanone; 1-Chloroacetone; 2-Propanone, 1-chloro-; 3-Chloro-2-propanone; Acetone, chloro-; Acetonyl chloride; Chloracetone [French]; Chloro-2-propanone; Chloroacetone; Chloromethyl methyl ketone; Chloropropanone; Monochloracetone; Monochloroacetone; Monochloropropanone; [ChemIDplus] UN1695
Category Other Toxic Gases & Vapors
Description Colorless to amber liquid with a pungent odor; [ACGIH]
Sources/Uses Used as a catalyst for polymerization and an intermediate for organic synthesis; Used in 1914 as a war gas; [ACGIH]
Comments A lacrimator, vesicant, and irritant of the respiratory tract; [ACGIH] Inhalation may cause acute pulmonary edema; [ICSC]
Exposure Assessment
Skin Designation (ACGIH) Yes
TIH Yes
Ceiling (ACGIH) 1 ppm
Vapor Pressure 12 mm Hg
Odor Threshold Low 0.02 ppm
Odor Threshold High 0.39 ppm
Lethal Concentration LC50 (rats) = 262 ppm/1H
Explanatory Notes Odor threshold from CHEMINFO; Boiling point = 248 degrees F (120 degrees C); Flash point = 82 degrees F; [CAMEO]
Adverse Effects
Toxic Pneumonitis Yes
Dermatotoxin Skin Burns
Lacrimator Yes
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: 1-CHLORO-2-PROPANONE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:





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Last updated: January, 2009