| Agent Name |
Hexachloroethane |
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| CAS Number |
67-72-1 |
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| Formula |
C2-Cl6 |
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| Major Category |
Other Classes |
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| Synonyms |
Carbon hexachloride; 1,1,1,2,2,2-Hexachloroethane; Avlothane; Distokal; Distopan; Distopin; Egitol; Ethane hexachloride; Ethane, hexachloro-; Ethylene hexachloride; Falkitol; Fasciolin; Fron 110; Hexachlor-aethan [German]; Hexachlorethane; Hexachloroethane; Hexachloroethylene; Mottenhexe; Perchloroethane; Phenohep; [ChemIDplus] UN9037 |
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| Category |
Halogenated Aliphatics |
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| Description |
Colorless crystals that sublime at 185 deg C and have a camphor-like odor; [Hawley] |
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| Sources/Uses |
Used by the military to make "smoke bombs" and by industry to remove air bubbles from molten aluminum; no longer produced in the United States; [ATSDR ToxFAQs] |
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| Comments |
Animals exposed to 48 ppm show no adverse effects except respiratory irritation. Feeding rats HCE for 16 weeks results in kidney and liver injury. [ACGIH] Has powerful narcotic effects; Also injures the liver and causes lacrimation on eye contact; [CAMEO] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
Yes |
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| TLV (ACGIH) |
1 ppm |
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| PEL (OSHA) |
1 ppm |
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| MAK |
1 ppm |
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| IDLH (NIOSH) |
300 ppm |
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| Excerpts from Documentation for IDLHs |
Based on the toxicological data relating to potential liver injury [Gleason et al. 1969; Elkins 1959], 300 ppm, the saturated vapor pressure at 20 C [Kirk�Othmer 1964] has been chosen as the IDLH. |
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| Vapor Pressure |
0.2 mm Hg |
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| Odor Threshold Low |
0.15 ppm |
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| Lethal Concentration |
LCLo (rats) = 5,900 ppm/8h |
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| Explanatory Notes |
Odor threshold from CHEMIINFO; |
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| Half Life |
Approximately 2.5 days; [HSDB] |
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| Reference Link |
ATSDR - ToxFAQs - Hexachloroethane |
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| Adverse Effects |
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| Neurotoxin |
Other CNS Neurotoxin |
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| Hepatotoxin |
Hepatotoxin, Secondary |
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| IARC Carcinogen |
Possible Carcinogen |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: HEXACHLOROETHANE
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