Agent Name |
Pyrogallol |
CAS Number |
87-66-1 |
Formula |
C6-H6-O3 |
Major Category |
Other Chemicals |
Synonyms |
1,2,3-Benzenetriol; 1,2,3-Trihydroxybenzen [Czech]; 1,2,3-Trihydroxybenzene; 215; Benzene, 1,2,3-trihydroxy-; C.I. 76515; C.I. Oxidation Base 32; CI 76515; CI Oxidation Base 32; Fouramine Brown AP; Fourrine 85; Fourrine PG; PYROGALLOL; Pyro; Pyrogallic acid; [ChemIDplus] UN8027 |
Category |
Phenols |
Description |
Odorless, white to gray solid; [CAMEO] |
Sources/Uses |
Used in photography and leather crafts; used in wool, fur, and hair dyeing; also used as an analytical chemistry reagent, an antioxidant for oils, and as a topical medication; [HSDB] Used in hair dyes and was used in photographic developers; [Kanerva, p. 1170] No longer used in hair dyes because of the frequency of allergic reactions; [Kanerva, p. 966] |
Comments |
Reported human toxicity after ingestion includes methemoglobinemia, hemolysis of red blood cells, and damage to the liver and kidneys. [HSDB] A potential skin sensitizer; [ICSC] Allergic contact dermatitis reported in hairdressers; [Kanerva, p. 1170] Mildly irritating to the skin; May cause serious eye irritation; [ICSC] Toxic by ingestion with adverse effects including convulsions; [CAMEO] May cause skin sensitization after prolonged contact; [ICSC] |
Reference Link |
Allergic reactions to a hairdressers' series: results from 9 European centres. The European Environmental and Contact Dermatitis Research Group (EECDRG) |
Exposure Assessment |
Skin Designation (ACGIH) |
Not evaluated |
Vapor Pressure |
0.000479 mm Hg |
Reference Link |
International Chemical Safety Cards (WHO/IPCS/ILO) |
Adverse Effects |
Methemoglobinemia |
Methemoglobinemia, Secondary |
Skin Sensitizer |
Yes |
Hepatotoxin |
Hepatotoxin, Secondary |
Links to Other NLM Databases |
Health Studies |
Human Health Effects from Hazardous Substances Data Bank: PYROGALLIC ACID
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